Concerted expansion and contraction of immune receptor gene repertoires in plant genomes.

Concerted expansion and contraction of immune receptor gene repertoires in plant genomes.
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DOI:
10.1038/s41477-022-01260-5
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发表时间:
2022-10
期刊:
影响因子:
18
通讯作者:
Jones, Jonathan Dg
Jones, Jonathan Dg
中科院分区:
生物学1区
文献类型:
--
作者:
Ngou, Bruno Pok Man;Heal, Robert;Wyler, Michele;Schmid, Marc W.;Jones, Jonathan Dg

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最近的报告表明,细胞表面和细胞内免疫受体协同作用,激活强大的防御病原体,但他们是否共同进化尚不清楚。在这里,我们确定了350个物种的细胞表面和细胞内免疫受体的数量。令人惊讶的是,预测编码细胞表面和细胞内免疫受体的受体基因的数量是强烈相关的。我们认为,这是一致的相互增强的免疫启动的细胞表面和细胞内的受体被反映在协调的共同进化的大小,其剧目在植物物种。对350种植物的比较基因组分析表明,细胞表面和细胞内免疫受体基因家族共同扩展或共同收缩。这表明植物免疫系统的两个分支之间存在进化关系。
Recent reports suggest that cell-surface and intracellular immune receptors function synergistically to activate robust defence against pathogens, but whether they co-evolve is unclear. Here we determined the numbers of cell-surface and intracellular immune receptors in 350 species. Surprisingly, the number of receptor genes that are predicted to encode cell-surface and intracellular immune receptors is strongly correlated. We suggest this is consistent with mutual potentiation of immunity initiated by cell-surface and intracellular receptors being reflected in the concerted co-evolution of the size of their repertoires across plant species. Comparative genomic analysis of 350 plant species reveals that cell-surface and intracellular immune receptor gene families co-expand or co-contract. This suggests an evolutionary relationship between the two branches of the plant immune system.
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影响因子: 5.6
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