Impact of apple and grape juice consumption on the antioxidant status in healthy subjects
Impact of apple and grape juice consumption on the antioxidant status in healthy subjects
复制标题
苹果和葡萄汁的摄入量对健康受试者抗氧化状态的影响
DOI：
10.3109/09637486.2011.587399
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发表时间：
2011-12
影响因子：
3.9
通讯作者：
Xiao, Rong
中科院分区：
文献类型：
--
作者：
Yuan, Linhong;Meng, Liping;Ma, Weiwei;Xiao, Zhongxin;Zhu, Xian;Feng, Jin Fang;Yu, Huanling;Xiao, Rong
据报道，食用富含抗氧化剂的食物可显著提高人体血浆总抗氧化能力（T-AOC）。此外，植物性食物中的抗氧化剂通过加和协同作用提高机体的抗氧化防御能力。因此，建议人们合理搭配富含抗氧化剂的食物，以预防氧化应激相关疾病。苹果和葡萄都是富含抗氧化剂的水果。本研究对25名健康受试者进行为期2周的饮食干预研究，探讨苹果汁和葡萄汁摄入对机体抗氧化状态的影响。我们的研究结果表明，2周的苹果汁和葡萄汁饮用增加了血浆T-AOC，降低了丙二醛浓度。血浆羰基含量未见明显变化。红细胞谷胱甘肽过氧化物酶和过氧化氢酶活性在饮用果汁2周后增强；红细胞超氧化物歧化酶活性未见明显变化。体外彗星试验结果表明，苹果汁和葡萄汁的摄入对过氧化氢处理对淋巴细胞的损伤没有影响。2周的果汁干预对尿8-羟基-2-脱氧鸟苷含量没有影响。这些发现表明，同时摄入苹果汁和葡萄汁可以有效地提高人体的抗氧化能力。
It is reported that consumption of antioxidant-rich foods significantly increased plasma total antioxidant capacity (T-AOC) in humans. Also, it is proved that the antioxidants from plant foods improve the body's antioxidant defence by acting additively and synergistically. As a result, rational combination of antioxidant-rich foods is recommended to population in the prevention of oxidative stress-related diseases. Both apple and grape are antioxidant-rich fruits. In this study, 2 weeks dietary intervention study was carried out in 25 healthy subjects to investigate the influences of apple and grape juices consumption on body antioxidant status. Our results indicated that 2 weeks of apple and grape juice consumption increased the plasma T-AOC and decreased the concentration of malondialdehyde. However, no change was found in the content of plasma carbonyl. Erythrocyte glutathione peroxidase and catalase activities were enhanced by 2 weeks of fruit juice consumption; however, no change was found in the activity of erythrocyte superoxide dismutase. The in vitro comet assay results indicated that apple and grape juice consumption did not influence lymphocyte damage upon hydrogen peroxide treatment. Urinary 8-hydroxy-2-deoxyguanosine content was not affected by 2 weeks of fruit juice intervention. These findings indicated that concomitant intake of apple and grape juice was efficient in enhancing the body's antioxidant status.
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DOI：
10.1093/ajcn/79.6.1060
发表时间：
2004-06
期刊：
The American journal of clinical nutrition
影响因子：
--
作者：
L. Dragsted;A. Pedersen;A. Hermetter;S. Basu;M. Hansen;G. R. Haren;M. Kall;V. Breinholt;J. Castenmiller;J. Stagsted;J. Jakobsen;L. Skibsted;S. E. Rasmussen;S. Loft;B. Sandström
通讯作者：
L. Dragsted;A. Pedersen;A. Hermetter;S. Basu;M. Hansen;G. R. Haren;M. Kall;V. Breinholt;J. Castenmiller;J. Stagsted;J. Jakobsen;L. Skibsted;S. E. Rasmussen;S. Loft;B. Sandström
影响因子：
2.4
作者：
A. Constantinou;G. Salti
通讯作者：
A. Constantinou;G. Salti
影响因子：
7.1
作者：
Nigdikar, SV;Williams, NR;Howard, AN
通讯作者：
Howard, AN
影响因子：
4.5
作者：
Guo, Changjiang;Wei, Jingyu;Jiang, Yugang
通讯作者：
Jiang, Yugang
影响因子：
6.1
作者：
Yang, Jun;Liu, Rui Hai
通讯作者：
Liu, Rui Hai