Uncertainty in mapping malaria epidemiology: implications for control.

Uncertainty in mapping malaria epidemiology: implications for control.
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绘制疟疾流行病学的不确定性:对控制的影响。

DOI:
10.1093/epirev/mxq013
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发表时间:
2010
影响因子:
5.5
通讯作者:
Sullivan,David
Sullivan,David
中科院分区:
医学3区
文献类型:
--
作者:
Sullivan,David

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疟疾是一种特定地点的动态传染病,由蚊子传播给人类,受环境、病媒、寄生虫和宿主因素的影响。疟疾流行病学的主要目的是1)描述疟疾在空间和时间上的分布以及物理、生物和社会致病因素;2)指导控制目标,以模拟影响或衡量控制策略的进展。从全球分布到人类、寄生虫和蚊子的生物数量性状定位,已经在许多不同的水平上实现了对疟疾及其许多致病因素的测绘。尽管取得了这些重要成就,但疟疾病例的年度负担仍然存在很大程度的不确定性。准确、灵敏地检测和治疗对传染病传播至关重要的无症状水库是未来控制措施所必需的额外组成部分。目前,在比尔和梅林达·盖茨的领导和资助下,疟疾社区正在制定和实施消灭疟疾的计划。疟疾专家面临的挑战是在空间和时间上对流行病因素和干预措施进行数字化整合和绘制地图,以便在进行研究工作的同时瞄准有效、可持续的控制措施。
Malaria is a location-specific, dynamic infectious disease transmitted by mosquitoes to humans and is influenced by environmental, vector, parasite, and host factors. The principal purposes of malarial epidemiology are 1) to describe the malarial distribution in space and time along with the physical, biologic, and social etiologic factors and 2) to guide control objectives for either modeling impact or measuring progress of control tactics. Mapping malaria and many of its causative factors has been achieved on many different levels from global distribution to biologic quantitative trait localization in humans, parasites, and mosquitoes. Despite these important achievements, a large degree of uncertainty still exists on the annual burden of malarial cases. Accurate, sensitive detection and treatment of asymptomatic reservoirs important to infectious transmission are additional components necessary for future control measures. Presently spurred by the leadership and funding of Bill and Melinda Gates, the malarial community is developing and implementing plans for elimination of malaria. The challenge for malariologists is to digitally integrate and map epidemiologic factors and intervention measures in space and time to target effective, sustainable control alongside research efforts.
DOI: 10.1186/1475-2875-9-37
发表时间: 2010-02-01
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影响因子: 3
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发表时间: 1949
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DOI: 10.1016/s0887-7963(98)80014-x
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期刊: MMWR. CDC surveillance summaries : Morbidity and mortality weekly report. CDC surveillance summaries
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期刊: Nature
影响因子: 64.8
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