The relationship between methamphetamine use and increased dental disease.
The relationship between methamphetamine use and increased dental disease.
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DOI：
10.14219/jada.archive.2010.0165
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发表时间：
2010-03
期刊：
影响因子：
--
通讯作者：
Rawson R
中科院分区：
文献类型：
--
作者：
Shetty V;Mooney LJ;Zigler CM;Belin TR;Murphy D;Rawson R
甲基苯丙胺（MA）的使用与猖獗的牙病有关。作者试图确定MA使用者中牙齿合并症的相对患病率，验证MA使用者是否有更多可量化的牙齿疾病和报告的牙齿问题，并确定MA给药模式对口腔健康结果的影响。参与的医生为依赖MA的成人提供了全面的医学和口腔评估（n = 301）。训练有素的采访者收集患者关于口腔健康和药物使用行为的自我报告。作者使用倾向评分匹配从第三次全国健康和营养检查调查（NHANES III）的参与者中创建了一个匹配的对照组。牙科或口腔疾病是MA使用者中最普遍的医疗合并症之一（41.3%），否则他们一般都很健康。平均而言，MA使用者比匹配的NHANES III对照参与者有更多的牙齿缺失（4.58对1.96,P < .001），更有可能报告有口腔健康问题（P < .001）。相当一部分MA使用者表示担心他们的牙齿外观（28.6%），牙齿断裂或松动（23.3%）以及牙齿磨牙（磨牙）或侵蚀（22.3%）。静脉注射MA比吸烟MA更有可能导致牙齿缺失（优势比= 2.47；95%可信区间= 1.3-4.8）。明显的牙齿疾病是鉴别MA使用者合并症的关键之一。MA使用者明显有较高的牙病发病率，并报告长期未满足的口腔健康需求。与通常的看法相反，吸烟或吸入MA的使用者比注射毒品的人患牙病的几率要低。许多MA使用者关心他们牙齿疾病的美容方面，这些担忧可以作为有针对性干预的行为触发因素。牙科疾病可以提供一个暂时稳定的MA特异性医学标记，在识别MA使用者方面具有区别效用。牙医可以在MA使用的早期发现中发挥关键作用，并参与MA用户的协作护理。
Methamphetamine (MA) use has been linked anecdotally to rampant dental disease. The authors sought to determine the relative prevalence of dental comorbidities in MA users, verify whether MA users have more quantifiable dental disease and report having more dental problems than nonusers and establish the influence of mode of MA administration on oral health outcomes. Participating physicians provided comprehensive medical and oral assessments for adults dependent on MA (n = 301). Trained interviewers collected patients' self-reports regarding oral health and substance-use behaviors. The authors used propensity score matching to create a matched comparison group of nonusers from participants in the the Third National Health and Nutrition Examination Survey (NHANES III). Dental or oral disease was one of the most prevalent (41.3 percent) medical cormorbidities in MA users who otherwise were generally healthy. On average, MA users had significantly more missing teeth than did matched NHANES III control participants (4.58 versus 1.96, P < .001) and were more likely to report having oral health problems (P < .001). Significant subsets of MA users expressed concerns with their dental appearance (28.6 percent), problems with broken or loose teeth (23.3 percent) and tooth grinding (bruxism) or erosion (22.3 percent). The intravenous use of MA was significantly more likely to be associated with missing teeth than was smoking MA (odds ratio = 2.47; 95 percent confidence interval = 1.3-4.8). Overt dental disease is one of the key distinguishing comorbidities in MA users. MA users have demonstrably higher rates of dental disease and report long-term unmet oral health needs. Contrary to common perception, users who smoke or inhale MA have lower rates of dental disease than do those who inject the drug. Many MA users are concerned with the cosmetic aspects of their dental disease, and these concerns could be used as behavioral triggers for targeted interventions. Dental disease may provide a temporally stable MA-specific medical marker with discriminant utility in identifying MA users. Dentists can play a crucial role in the early detection of MA use and participate in the collaborative care of MA users.
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影响因子：
2.9
作者：
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通讯作者：
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3.2
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