Merge in the Human Brain: A Sub-Region Based Functional Investigation in the Left Pars Opercularis
Merge in the Human Brain: A Sub-Region Based Functional Investigation in the Left Pars Opercularis
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人脑中的合并：基于子区域的左眼盖部功能研究
DOI：
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发表时间：
2015
影响因子：
3.8
通讯作者：
A. Friederici
中科院分区：
文献类型：
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作者：
E. Zaccarella;A. Friederici
语言被认为是人类最复杂的认知功能之一。在这里，我们将语言的复杂性分解为最基本的句法计算，这种计算将单个单词分层绑定在一起，形成更大的短语和句子。到目前为止，这一基本操作的神经实现只是从研究更复杂的语言现象的研究中间接推断出来的。在目前的分区功能磁共振成像（fMRI）研究中，我们直接评估了这个过程的神经解剖学性质。我们的研究结果表明，句法短语相比，单词列表序列，对应于增加的神经活动在腹前部分的左部鳃盖[布罗德曼区（BA）44]，而相邻的位于深额鳃盖/前额叶（FOP/aINS），一个遗传年龄较大，专业化程度较低的地区，被认为是同样活跃的两种条件。至关重要的是，句法结合的功能活动被限制在最近提出的细粒度的亚解剖parcellation BA 44的五个集群之一，与个人之间的一致性。神经解剖学上，目前的结果要求重新定义BA 44作为一个区域与内部功能专业化。从神经计算的角度来看，他们支持BA 44在参与者的激活位置中不变性的想法，用于基本的句法构建处理。
Language is thought to represent one of the most complex cognitive functions in humans. Here we break down complexity of language to its most basic syntactic computation which hierarchically binds single words together to form larger phrases and sentences. So far, the neural implementation of this basic operation has only been inferred indirectly from studies investigating more complex linguistic phenomena. In the present sub-region based functional magnetic resonance imaging (fMRI) study we directly assessed the neuroanatomical nature of this process. Our results showed that syntactic phrases—compared to word-list sequences—corresponded to increased neural activity in the ventral-anterior portion of the left pars opercularis [Brodmann Area (BA) 44], whereas the adjacently located deep frontal operculum/anterior insula (FOP/aINS), a phylogenetically older and less specialized region, was found to be equally active for both conditions. Crucially, the functional activity of syntactic binding was confined to one out of five clusters proposed by a recent fine-grained sub-anatomical parcellation for BA 44, with consistency across individuals. Neuroanatomically, the present results call for a redefinition of BA 44 as a region with internal functional specializations. Neurocomputationally, they support the idea of invariance within BA 44 in the location of activation across participants for basic syntactic building processing.
影响因子：
3.7
作者：
Downing, P. E.;Chan, A. W. -Y.;Kanwisher, N.
通讯作者：
Kanwisher, N.
失语症的动作理解：语言和非语言缺陷及其病变相关性。
影响因子：
2.6
作者：
Saygin,AysePinar;Wilson,StephenM;Dronkers,NinaF;Bates,Elizabeth
通讯作者：
Bates,Elizabeth