The human connectome: A structural description of the human brain.

The human connectome: A structural description of the human brain.
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人类连接:人脑的结构描述。

DOI:
10.1371/journal.pcbi.0010042
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发表时间:
2005-09
影响因子:
4.3
通讯作者:
Kötter R
Kötter R
中科院分区:
生物学2区
文献类型:
--
作者:
Sporns O;Tononi G;Kötter R

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人类大脑的连接矩阵(人类的“连接组”)是基础和应用神经生物学研究不可或缺的基础。然而,连接人类大脑神经元要素的解剖连接网络在很大程度上仍然未知。虽然存在一些其他哺乳动物物种的大规模解剖连接模式的数据库或资料整理,但目前没有人类大脑的连接矩阵,也没有协调一致的研究工作来收集、存档和传播这一重要信息。我们提出了一种实现这一目标的研究策略,并讨论了其潜在影响。
The connection matrix of the human brain (the human “connectome”) represents an indispensable foundation for basic and applied neurobiological research. However, the network of anatomical connections linking the neuronal elements of the human brain is still largely unknown. While some databases or collations of large-scale anatomical connection patterns exist for other mammalian species, there is currently no connection matrix of the human brain, nor is there a coordinated research effort to collect, archive, and disseminate this important information. We propose a research strategy to achieve this goal, and discuss its potential impact.
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