Advances and Perspectives on the Epidemiology of Bovine Cryptosporidium in China in the Past 30 Years.
Advances and Perspectives on the Epidemiology of Bovine Cryptosporidium in China in the Past 30 Years.
复制标题
近30年我国牛隐孢子虫流行病学研究进展与展望
DOI：
10.3389/fmicb.2017.01823
复制
发表时间：
2017
影响因子：
5.2
通讯作者：
Zhang L
中科院分区：
文献类型：
--
作者：
Wang R;Zhao G;Gong Y;Zhang L
近30年来，我国对牛隐孢子虫的流行病学研究取得了重大进展。总感染率为14.50%（5265/36316），其中奶牛、牦牛、肉牛和布法罗的感染率不同。感染率随动物年龄的增长而下降，冬季感染率最低。牛隐孢子虫有10个种和2个基因型，其中微小隐孢子虫（Cryptosporidiumparvum）、隐孢子虫C. andersoni，C. bovis和C. ryanae是最常见的物种。牛隐孢子虫（Cryptosporidiumbovis）而不是C. parvum在断奶前奶牛中占优势，C.在奶牛中检测到的亚型仅为微小型IIdA 15 G1和IIdA 19 G1。在牦牛中发现了IIa和IId两个亚型家族。群体遗传学分析表明，该菌具有流行性的群体结构. andersoni，提示C. andersoni在中国是不是由于引进奶牛。此外，C.根据来自中国、瑞典和埃及的分离株的群体遗传学分析，parvum IId亚型可能从西亚分散到其他地理区域。因此，我们推测隐孢子虫是在过去传入中国的，并且在不同的宿主中逐渐形成不同的种群，这些因素包括传播动力学、地理隔离、宿主特异性和大规模养殖。需要更多的流行病学研究来验证这一假设，并澄清隐孢子虫在中国的流行和传播。
Major progress has been made in understanding the epidemiology of bovine Cryptosporidium in China in the past 30 years. The overall infection rate in that period was 14.50% (5265/36316), with different prevalence being observed among dairy cattle, yaks, beef cattle, and buffalo. The infection rate declined as the animals’ ages increased and the lowest prevalence occurred in winter. Ten Cryptosporidium species and two genotypes have been found in cattle, with Cryptosporidium parvum, C. andersoni, C. bovis, and C. ryanae being the commonest species. Cryptosporidium bovis rather than C. parvum predominated in preweaned dairy cattle, and C. parvum IIdA15G1 and IIdA19G1 were the only subtypes detected in dairy cattle. Two subtype families, IIa and IId, were found in yaks. Population genetic analysis detected an epidemic population structure in C. andersoni, which suggested that the prevalence of C. andersoni in China is not attributable to the introduction of dairy cattle. Moreover, C. parvum IId subtypes probably dispersed from western Asia to other geographic regions based on population genetic analysis of isolates from China, Sweden, and Egypt. Therefore, we hypothesize that Cryptosporidium was introduced into China in the past, and different populations formed progressively in various hosts in response to diverse factors, including the transmission dynamics, geographic isolation, host specificity, and large-scale farming. More epidemiological studies are required to test this hypothesis and to clarify the prevalence and transmission of Cryptosporidium species in China.
登录
查看更多内容
影响因子：
11.8
作者：
Feng Y;Wang L;Duan L;Gomez-Puerta LA;Zhang L;Zhao X;Hu J;Zhang N;Xiao L
通讯作者：
Xiao L
影响因子：
11.8
作者：
Li N;Xiao L;Alderisio K;Elwin K;Cebelinski E;Chalmers R;Santin M;Fayer R;Kvac M;Ryan U;Sak B;Stanko M;Guo Y;Wang L;Zhang L;Cai J;Roellig D;Feng Y
通讯作者：
Feng Y
影响因子：
3.2
作者：
Qin SY;Zhang XX;Zhao GH;Zhou DH;Yin MY;Zhao Q;Zhu XQ
通讯作者：
Zhu XQ
影响因子：
168.9
作者：
Kotloff, Karen L.;Nataro, James P.;Levine, Myron M.
通讯作者：
Levine, Myron M.
影响因子：
3.5
作者：
ESTEBAN, E;ANDERSON, BC
通讯作者：
ANDERSON, BC