Facile synthesis and in vitro bioactivity of radial mesoporous bioactive glasses

Facile synthesis and in vitro bioactivity of radial mesoporous bioactive glasses
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径向介孔生物活性玻璃的简易合成及其体外生物活性

DOI:
10.1016/j.matlet.2017.07.021
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发表时间:
2017-11
期刊:
影响因子:
3
通讯作者:
Chen Xiaofeng
Chen Xiaofeng
中科院分区:
材料科学3区
文献类型:
--
作者:
Wang Yudong;Liao Tianshun;Shi Miao;Liu Cong;Chen Xiaofeng

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本文报道了一种利用十六烷基三甲基溴化铵(CTAB)胶束作为反应中心制备径向介孔生物活性玻璃(RMBG)的简便方法。放射状结构是由溶解在疏水性溶剂(环己烷)中的前体延伸形成的,聚集在CTAB胶束的内部。通过多种方法研究了RMBGs的形态、结构和体外生物活性。结果表明,CTAB胶束可以限制前驱体溶解的环己烷,有利于制备具有放射状介孔结构、高比表面积和良好磷灰石形成能力的RMBGs。所获得的具有新颖结构和性能的RMBGs可能在药物输送和硬组织再生方面具有潜在的应用。
This paper reports a facile method for fabricating radial mesoporous bioactive glasses (RMBGs) using Hexadecyl trimethyl ammonium bromide (CTAB) micelle as the reaction center. The radial structure was formed with the extension of precursor dissolved in the hydrophobic solvent (cyclohexane) which gathered in the internal part of the CTAB micelle. The morphology, structure and in vitro bioactivity of RMBGs were investigated by various methods. The results indicate that the CTAB micelle could restrict the precursor-dissolved cyclohexane and was in favor of preparing the RMBGs with radial mesoporous structure, high specific surface area and good apatite-forming ability. The obtained RMBGs with the novel structure and properties may have potential application in drug delivery and hard tissue regeneration.
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