Cubic membranes: a legend beyond the Flatland* of cell membrane organization.
Cubic membranes: a legend beyond the Flatland* of cell membrane organization.
复制标题
立方膜:细胞膜组织的扁平地*之外的传奇。
DOI:
10.1083/jcb.200603055
复制
发表时间:
2006-06-19
影响因子:
7.8
通讯作者:
Deng, Yuru
中科院分区:
文献类型:
--
作者:
Almsherqi, Zakaria A.;Kohlwein, Sepp D.;Deng, Yuru
Cubic membranes represent highly curved, three-dimensional nanoperiodic structures that correspond to mathematically well defined triply periodic minimal surfaces. Although they have been observed in numerous cell types and under different conditions, particularly in stressed, diseased, or virally infected cells, knowledge about the formation and function of nonlamellar, cubic structures in biological systems is scarce, and research so far is restricted to the descriptive level. We show that the “organized smooth endoplasmic reticulum” (OSER; Snapp, E.L., R.S. Hegde, M. Francolini, F. Lombardo, S. Colombo, E. Pedrazzini, N. Borgese, and J. Lippincott-Schwartz. 2003. J. Cell Biol. 163:257–269), which is formed in response to elevated levels of specific membrane-resident proteins, is actually the two-dimensional representation of two subtypes of cubic membrane morphology. Controlled OSER induction may thus provide, for the first time, a valuable tool to study cubic membrane formation and function at the molecular level.
登录
查看更多内容
影响因子:
7.8
作者:
LUZZATI, V;HUSSON, F
通讯作者:
HUSSON, F
影响因子:
2.9
作者:
Deng, YR;Kohlwein, SD;Mannella, CA
通讯作者:
Mannella, CA
影响因子:
2.9
作者:
Deng, YR;Mieczkowski, M
通讯作者:
Mieczkowski, M
影响因子:
3
作者:
Hsieh, CE;Leith, A;Marko, M
通讯作者:
Marko, M
影响因子:
3.8
作者:
Almsherqi, ZA;McLachlan, CS;Deng, Y
通讯作者:
Deng, Y