The influence of age of onset and acute anabolic steroid exposure on cognitive performance, impulsivity, and aggression in men.
The influence of age of onset and acute anabolic steroid exposure on cognitive performance, impulsivity, and aggression in men.
复制标题
DOI：
10.1037/a0036482
复制
发表时间：
2014-12
期刊：
影响因子：
--
通讯作者：
Berlin HA
中科院分区：
文献类型：
--
作者：
Hildebrandt T;Langenbucher JW;Flores A;Harty S;Berlin HA
A growing translational literature suggests that adolescent exposure to anabolic-androgenic steroids (AASs) leads to increased aggression and impulsivity. However, little is known about the cognitive effects of AASs among AAS users or the differences between adolescent and adult onset users. This study provides a test of the effects of acute naturalistic AAS use and age of onset (adolescent vs. adult) on measures of inhibitory control, planning and attention, and decision making. Seventy one active adult male AAS uses completed self-report measures of impulsivity and aggress and a subsample (11 adolescent onset vs. 11 adult onset) matched on current age were administered four computerized test from the CANTAB battery and the Iowa Gambling Task. Multiple regression analyses and a series of 2 (Adolescent vs. Adult) X 2 (On-cycle vs. Off-cycle) analyses of variance (ANOVAs) were used to examine the differential effects of age of onset and acute drug use on cognition and behavior. Regression analyses revealed larger on-cycle effects for adolescent users than adult users. Subsample analyses indicated that on-cycle users performed less well on cognitive measures of inhibitory control and attention, but not on tests of planning or decision making. Adolescent onset was associated with a greater impulsivity and a greater acute sensitivity to AAS effects on attention. These preliminary findings suggest the possibility that acute AAS use is associated with some differences in inhibitory control and impulsivity and to a lesser degree aggression. These effects may be more potent for those initiating AAS use in adolescence.
登录
查看更多内容
影响因子：
3.7
作者：
Bramen JE;Hranilovich JA;Dahl RE;Chen J;Rosso C;Forbes EE;Dinov ID;Worthman CM;Sowell ER
通讯作者：
Sowell ER
影响因子：
2.5
作者：
Ambar, G.;Chiavegatto, S.
通讯作者：
Chiavegatto, S.
影响因子：
3.4
作者：
Hildebrandt, Tom;Langenbucher, James;Park, Steff
通讯作者：
Park, Steff
影响因子：
3.5
作者：
Farrell, SF;McGinnis, MY
通讯作者：
McGinnis, MY
影响因子：
3.5
作者：
Cunningham, Rebecca L.;Lumia, Augustus R.;McGinnis, Marilyn Y.
通讯作者：
McGinnis, Marilyn Y.