Validating the theoretical bases of sleep reactivation during sharp‐wave ripples and their association with emotional valence
Validating the theoretical bases of sleep reactivation during sharp‐wave ripples and their association with emotional valence
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验证锐波波动期间睡眠重新激活的理论基础及其与情绪效价的关联
DOI：
10.1002/hipo.23143
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发表时间：
2020
期刊：
影响因子：
3.5
通讯作者：
K. Benchenane
中科院分区：
文献类型：
--
作者：
S. Laventure;K. Benchenane
睡眠对记忆巩固很重要，大量文献表明，睡眠期间海马体的重新激活有助于这一过程。然而，目前对尖波波纹（SWR）期间活动的解释，作为唤醒经验的重演，依赖于假设，虽然被广泛接受，但最近才开始直接测试。此外，这一理论主要是在纯空间学习的背景下研究的，目前还不清楚在考虑基于奖励或惩罚的学习时，情绪效价如何适应这一概念框架。在这篇综述中，我们将提出最近的实验参数验证的解释睡眠重播唤醒经验的重新激活，并检查证据表明，情绪效价也重播在睡眠中与海马体的SWR协调的方式。最后，我们将详细介绍最近的实验表明，脑机接口可以用来修改与睡眠重放相关的情绪效价。
Sleep is important for memory consolidation, and an abundant literature suggests that reactivation in the hippocampus during sleep is instrumental to this process. Yet, the current interpretation of activity during sharp‐waves ripples (SWRs), as replay of wake experiences, relies on hypotheses that, while widely accepted, have only recently begun to be tested directly. Moreover, this theory has been mainly studied in the context of pure spatial learning, and it is still not clear how emotional valence can fit into this conceptual framework when considering reward‐ or punishment‐based learning. In this review, we will present recent experimental arguments validating the interpretation of sleep replay as reactivation of awake experiences and examine the evidence showing that the emotional valence is also replayed during sleep in a coordinated fashion with hippocampal SWRs. Finally, we will detail recent experiments showing that brain–computer interfaces can be used to modify the emotional valence associated with sleep replay.
影响因子：
56.9
作者：
WILSON, MA;MCNAUGHTON, BL
通讯作者：
MCNAUGHTON, BL
DOI：
10.1101/sqb.2014.79.024679
发表时间：
2014
期刊：
Cold Spring Harbor symposia on quantitative biology
影响因子：
--
作者：
Buzsáki G;Peyrache A;Kubie J
通讯作者：
Kubie J