A femtosecond laser inscribed biochip for stem cell therapeutic applications

A femtosecond laser inscribed biochip for stem cell therapeutic applications
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用于干细胞治疗应用的飞秒激光刻印生物芯片

DOI:
10.1117/12.874954
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发表时间:
2011
期刊:
--
影响因子:
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通讯作者:
Choudhury D
Choudhury D
中科院分区:
--
文献类型:
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作者:
Choudhury D

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设计并制作了一个连续流动的微流控细胞分离平台。该装置是一种可扩展的非侵入性细胞分离机制,旨在基于细胞骨架弹性的差异将人胚胎干细胞与分化细胞分离。该装置的成功演示已经使用人类白血病细胞实现,其弹性类似于人类胚胎干细胞。
A continuous flow microfluidic cell separation platform has been designed and fabricated using femtosecond laser inscription. The device is a scalable and non-invasive cell separation mechanism aimed at separating human embryonic stem cells from differentiated cells based on the dissimilarities in their cytoskeletal elasticity. Successful demonstration of the device has been achieved using human leukemia cells the elasticity of which is similar to that of human embryonic stem cells.
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