Role of commensal and probiotic bacteria in human health: a focus on inflammatory bowel disease.
Role of commensal and probiotic bacteria in human health: a focus on inflammatory bowel disease.
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DOI：
10.1186/1475-2859-12-71
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发表时间：
2013-07-23
影响因子：
6.4
通讯作者：
Bermúdez-Humarán LG
中科院分区：
文献类型：
--
作者：
Martín R;Miquel S;Ulmer J;Kechaou N;Langella P;Bermúdez-Humarán LG
人类肠道是最复杂的生态系统之一，由1013-1014个微生物组成，对人类健康起着重要作用。此外，有些食品含有活细菌，它们会通过我们的胃肠道，对我们的健康产生有益的影响（称为益生菌效应）。在众多的健康益处中，益生菌和益生菌与宿主免疫系统相互作用的能力现在得到了很好的证明。目前，作为益生菌概念的延伸，使用重组乳酸菌来递送具有健康意义的化合物正变得越来越重要。本文综述了近年来益生菌和益生菌与宿主细胞相互作用的研究进展，以及重组益生菌和益生菌的最新研究进展。我们的目的是突出重组细菌在这个生态系统中的潜在作用。
The human gut is one of the most complex ecosystems, composed of 1013-1014 microorganisms which play an important role in human health. In addition, some food products contain live bacteria which transit through our gastrointestinal tract and could exert beneficial effects on our health (known as probiotic effect). Among the numerous proposed health benefits attributed to commensal and probiotic bacteria, their capacity to interact with the host immune system is now well demonstrated. Currently, the use of recombinant lactic acid bacteria to deliver compounds of health interest is gaining importance as an extension of the probiotic concept. This review summarizes some of the recent findings and perspectives in the study of the crosstalk of both commensal and probiotic bacteria with the human host as well as the latest studies in recombinant commensal and probiotic bacteria. Our aim is to highlight the potential roles of recombinant bacteria in this ecosystem.
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影响因子：
11.1
作者：
Amar, Jacques;Chabo, Chantal;Waget, Aurelie;Klopp, Pascale;Vachoux, Christelle;Bermudez-Humaran, Luis G.;Smirnova, Natalia;Berge, Mathieu;Sulpice, Thierry;Lahtinen, Sampo;Ouwehand, Arthur;Langella, Philippe;Rautonen, Nina;Sansonetti, Philippe J.;Burcelin, Remy
通讯作者：
Burcelin, Remy
影响因子：
3.7
作者：
Armougom F;Henry M;Vialettes B;Raccah D;Raoult D
通讯作者：
Raoult D
影响因子：
3
作者：
Bermúdez-Humarán, LG;Cortes-Perez, NG;Langella, P
通讯作者：
Langella, P
影响因子：
4.6
作者：
Böcker, U;Nebe, T;Singer, MV
通讯作者：
Singer, MV
影响因子：
4.4
作者：
Bermudez-Humaran, Luis G.;Nouaille, Sebastien;Issad, Tarik
通讯作者：
Issad, Tarik