Validity and reproducibility of folate and vitamin B(12) intakes estimated from a self-administered diet history questionnaire in Japanese pregnant women.

Validity and reproducibility of folate and vitamin B(12) intakes estimated from a self-administered diet history questionnaire in Japanese pregnant women.
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DOI:
10.1186/1475-2891-11-15
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发表时间:
2012-03-15
期刊:
影响因子:
5.4
通讯作者:
Murashima S
Murashima S
中科院分区:
医学2区
文献类型:
--
作者:
Shiraishi M;Haruna M;Matsuzaki M;Murayama R;Sasaki S;Murashima S

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在日本,没有有效的饮食问卷来评估怀孕期间叶酸和维生素B12的摄入量。我们评估了日本孕妇自填饮食历史问卷(DHQ)估计的叶酸和维生素B12摄入量的有效性和重复性。2008年6月至10月在东京都的一家私立产科医院招募了167名怀孕中期单胎妊娠的健康受试者(n=76),2010年6月至2011年6月在东京的一所大学医院招募了(n=91)。用DHQ评估膳食中叶酸和维生素B12的摄入量。在验证性研究中,测定血清叶酸和维生素B12浓度作为参考值。为了评估结果的重复性,58名孕妇在4-5周的间隔内完成了两次DHQ。能量调整摄入量与血清叶酸和维生素B12浓度呈显著正相关(r=0.286,p=0.001和r=0.222,p=0.004)。排除有恶心症状的参与者(n=121)后,维生素B12的相关系数增加到0.313(p=0.001)。当参与者根据叶酸和维生素B12的摄入量和血清浓度被分为五分位数时,大约60%的人被归类为相同或相邻的五分位数。两次DHQ的组内相关系数叶酸为0.725,维生素B12为0.512。本研究表明,DHQ在评估日本孕妇叶酸和维生素B12摄入量方面具有可接受的效度和重复性。
No validated dietary questionnaire for assessing folate and vitamin B12 intakes during pregnancy is available in Japan. We evaluated the validity and reproducibility of intakes of folate and vitamin B12 estimated from a self-administered diet history questionnaire (DHQ) in Japanese pregnant women. A sample of 167 healthy subjects with singleton pregnancies in the second trimester was recruited at a private obstetric hospital in metropolitan Tokyo from June to October 2008 (n = 76), and at a university hospital in Tokyo from June 2010 to June 2011 (n = 91). The dietary intakes of folate and vitamin B12 were assessed using the DHQ. The serum concentrations of folate and vitamin B12 were measured as reference values in the validation study. To assess the reproducibility of the results, 58 pregnant women completed the DHQ twice within 4-5 week interval. Significantly positive correlations were found between energy-adjusted intakes and serum concentrations of folate and vitamin B12 (r = 0.286, p < 0.001 and r = 0.222, p = 0.004, respectively). After excluding the participants with nausea (n = 121), the correlation coefficient for vitamin B12 increased to 0.313 (p = 0.001). When participants were classified into quintiles based on intakes and serum concentrations of folate and vitamin B12 , approximately 60% were classified in the same or adjacent quintile. The intraclass correlation coefficients of the two-time DHQ were 0.725 for folate and 0.512 for vitamin B12 . The present study indicated that the DHQ had acceptable validity and reproducibility for assessing folate and vitamin B12 intakes in Japanese pregnant women.
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发表时间: 2000-12-01
影响因子: 1.6
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