Sleep Apnea and Nocturnal Cardiac Arrhythmia: A Populational Study.
Sleep Apnea and Nocturnal Cardiac Arrhythmia: A Populational Study.
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睡眠呼吸暂停和夜间心律不齐：人口研究。
DOI：
10.5935/abc.20140142
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发表时间：
2014-11
影响因子：
2.6
通讯作者：
Paola AD
中科院分区：
文献类型：
--
作者：
Cintra FD;Leite RP;Storti LJ;Bittencourt LA;Poyares D;Castro LD;Tufik S;Paola AD
与阻塞性睡眠呼吸暂停的心血管后果相关的机制包括自主神经张力的突然变化，这可能引发心律失常。作者假设阻塞性睡眠呼吸暂停患者夜间心律失常发生率更高。分析人群样本中阻塞性睡眠呼吸暂停与睡眠期心律异常的关系。横断面研究与1,101名志愿者，谁形成了圣保罗市的代表性样本。在个体的常规睡眠时间表期间，使用EMBLA® S7000数字系统进行过夜多导睡眠描记。提取、复制心电图通道，然后使用霍尔特（Cardio Smart®）系统进行分析。共有767名参与者（461名男性）被纳入分析，平均年龄为42.00 ± 0.53岁。在62.7%的样本中观察到至少一种类型的夜间心律失常（房性/室性心律失常或搏动）。夜间心律失常的发生率随着疾病严重程度的增加而增加。53.3%的无呼吸睡眠障碍的患者存在心律失常，而92.3%的重度阻塞性睡眠呼吸暂停患者存在心律失常。与对照组相比，中/重度阻塞性睡眠呼吸暂停患者孤立性心房和心室异位更常见（p < 0.001）。在控制了潜在的混杂因素后，年龄、性别和呼吸暂停低通气指数与夜间心律失常相关。阻塞性睡眠呼吸暂停综合征患者夜间心律失常的发生率更高，患病率随疾病严重程度的增加而增加。年龄、性别和呼吸暂停低通气指数是该样本中心律失常的预测因素。
The mechanisms associated with the cardiovascular consequences of obstructive sleep apnea include abrupt changes in autonomic tone, which can trigger cardiac arrhythmias. The authors hypothesized that nocturnal cardiac arrhythmia occurs more frequently in patients with obstructive sleep apnea. To analyze the relationship between obstructive sleep apnea and abnormal heart rhythm during sleep in a population sample. Cross-sectional study with 1,101 volunteers, who form a representative sample of the city of São Paulo. The overnight polysomnography was performed using an EMBLA® S7000 digital system during the regular sleep schedule of the individual. The electrocardiogram channel was extracted, duplicated, and then analyzed using a Holter (Cardio Smart®) system. A total of 767 participants (461 men) with a mean age of 42.00 ± 0.53 years, were included in the analysis. At least one type of nocturnal cardiac rhythm disturbance (atrial/ventricular arrhythmia or beat) was observed in 62.7% of the sample. The occurrence of nocturnal cardiac arrhythmias was more frequent with increased disease severity. Rhythm disturbance was observed in 53.3% of the sample without breathing sleep disorders, whereas 92.3% of patients with severe obstructive sleep apnea showed cardiac arrhythmia. Isolated atrial and ventricular ectopy was more frequent in patients with moderate/severe obstructive sleep apnea when compared to controls (p < 0.001). After controlling for potential confounding factors, age, sex and apnea-hypopnea index were associated with nocturnal cardiac arrhythmia. Nocturnal cardiac arrhythmia occurs more frequently in patients with obstructive sleep apnea and the prevalence increases with disease severity. Age, sex, and the Apnea-hypopnea index were predictors of arrhythmia in this sample.
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影响因子：
3
作者：
Paulino, Alexandra;Damy, Thibaud;d'Ortho, Marie-Pia
通讯作者：
d'Ortho, Marie-Pia
影响因子：
4.8
作者：
Olmetti, Francesca;La Rovere, Maria Teresa;Fanfulla, Francesco
通讯作者：
Fanfulla, Francesco
DOI：
10.1136/hrt.2009.173625
发表时间：
2009-11
期刊：
Heart (British Cardiac Society)
影响因子：
--
作者：
Oliveira W;Campos O;Cintra F;Matos L;Vieira ML;Rollim B;Fujita L;Tufik S;Poyares D
通讯作者：
Poyares D
影响因子：
120.7
作者：
Nieto, FJ;Young, TB;Pickering, TG
通讯作者：
Pickering, TG
影响因子：
4.4
作者：
Pitson, DJ;Stradling, JR
通讯作者：
Stradling, JR