Region II of the Haemophilus influenzae Type b capsulation locus as involved in serotype‐specific polysaccharide synthesis
Region II of the Haemophilus influenzae Type b capsulation locus as involved in serotype‐specific polysaccharide synthesis
复制标题
b 型流感嗜血杆菌荚膜位点 II 区参与血清型特异性多糖合成
作者:
J. Eldere;L. Brophy;B. Loynds;Patrick Celts;I. Hancock;Stephen Carman;J. Kroll;E. Moxon
The central (serotype‐specific) Region II of the Haemophilus influenzae Type b capsulation locus cap is 8.3 kb long and contains a cluster of four genes. We show that these genes, designated orf1 to orf4, are involved in the biosynthetic steps required for the formation of the Type b capsular polysaccharide and that orf1 probably encodes a CDP‐ribitolpyrophosphorylase. We present evidence that growth of polysaccharide chains takes place through the alternating addition of single sugar nucleotides.
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DOI:
--
发表时间:
1984
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Whitfield,C;Adams,DA;Troy,FA
通讯作者:
Troy,FA
影响因子:
3.5
作者:
DANNER, DB;DEICH, RA;SMITH, HO
通讯作者:
SMITH, HO
DOI:
10.1172/jci111214
发表时间:
1984
期刊:
The Journal of clinical investigation
影响因子:
--
作者:
Moxon,ER;Deich,RA;Connelly,C
通讯作者:
Connelly,C
影响因子:
2.9
作者:
PAYNE, SM;AMES, BN
通讯作者:
AMES, BN