Relationship between smoking and obesity: a cross-sectional study of 499,504 middle-aged adults in the UK general population.
Relationship between smoking and obesity: a cross-sectional study of 499,504 middle-aged adults in the UK general population.
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DOI：
10.1371/journal.pone.0123579
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Pell JP
中科院分区：
文献类型：
--
作者：
Dare S;Mackay DF;Pell JP
人们普遍认为，吸烟可以防止体重增加，这可能会影响吸烟的开始和继续，特别是在年轻女性中。使用英国生物库的基线数据进行了一项横断面研究。用Logistic回归分析探讨吸烟与肥胖之间的关系；肥胖定义为体重指数(BMI)和30公斤/平方米。根据吸烟状况、吸烟量、吸烟持续时间和戒烟时间进行检查，并调整了年龄、性别、社会经济剥夺、体力活动、饮酒、高血压和糖尿病等潜在的混杂影响。这项研究涉及499,504名年龄在31岁至69岁之间的成年人。总体而言，现在吸烟者比从不吸烟者肥胖的可能性更小(调整后的OR为0.83，95%CI为0.81-0.86)。然而，在最年轻的亚组(≤40岁)中没有显著的相关性。既往吸烟者肥胖的可能性高于现在吸烟者(调整后OR 1.33 95%CI 1.30~1.37)和从不吸烟者(调整后OR 1.14 95%CI 1.12~1.15)。在吸烟者中，肥胖的风险随着吸烟量的增加而增加，并且以前重度吸烟者比以前轻度吸烟者更容易肥胖(调整后的OR1.6，95%1.56-1.64，p<；0.001)。从戒烟开始，肥胖风险随着时间的推移而下降。30年后，曾经吸烟者患肥胖症的风险仍然高于现在吸烟者，但与从不吸烟者的风险相同。认为吸烟可以预防肥胖的观点可能过于简单化了；尤其是在年轻和重度吸烟者中。戒烟可能与暂时的体重增加有关。因此，戒烟干预应包括体重管理支持。
There is a general perception that smoking protects against weight gain and this may influence commencement and continuation of smoking, especially among young women. A cross-sectional study was conducted using baseline data from UK Biobank. Logistic regression analyses were used to explore the association between smoking and obesity; defined as body mass index (BMI) >30kg/m2. Smoking was examined in terms of smoking status, amount smoked, duration of smoking and time since quitting and we adjusted for the potential confounding effects of age, sex, socioeconomic deprivation, physical activity, alcohol consumption, hypertension and diabetes. The study comprised 499,504 adults aged 31 to 69 years. Overall, current smokers were less likely to be obese than never smokers (adjusted OR 0.83 95% CI 0.81-0.86). However, there was no significant association in the youngest sub-group (≤40 years). Former smokers were more likely to be obese than both current smokers (adjusted OR 1.33 95% CI 1.30-1.37) and never smokers (adjusted OR 1.14 95% CI 1.12-1.15). Among smokers, the risk of obesity increased with the amount smoked and former heavy smokers were more likely to be obese than former light smokers (adjusted OR 1.60, 95% 1.56-1.64, p<0.001). Risk of obesity fell with time from quitting. After 30 years, former smokers still had higher risk of obesity than current smokers but the same risk as never smokers. Beliefs that smoking protects against obesity may be over-simplistic; especially among younger and heavier smokers. Quitting smoking may be associated with temporary weight gain. Therefore, smoking cessation interventions should include weight management support.
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影响因子：
5.9
作者：
Meyers, AW;Klesges, RC;Eck, LH
通讯作者：
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影响因子：
4.7
作者：
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影响因子：
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作者：
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DOI：
10.3390/ijerph6030943
发表时间：
2009-03-01
影响因子：
--
作者：
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通讯作者：
West, Robert
影响因子：
27.4
作者：
HELLIWELL, PS;JACKSON, S
通讯作者：
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