4D flow MRI in abdominal vessels: prospective comparison of k-t accelerated free breathing acquisition to standard respiratory navigator gated acquisition.
4D flow MRI in abdominal vessels: prospective comparison of k-t accelerated free breathing acquisition to standard respiratory navigator gated acquisition.
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DOI：
10.1038/s41598-022-23864-9
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发表时间：
2022-11-18
影响因子：
4.6
通讯作者：
中科院分区：
文献类型：
--
作者：
三维速度编码的体积相对比磁共振成像（4D flow MRI）已被证明是一种非侵入性工具，可用于检查慢性肝病的血流改变。具有时空加速特性的新型四维流MRI脉冲序列可以缓解标准四维流MRI采集时间过长对临床应用的阻碍。我们研究的目的是证明自由呼吸、时空（k−t）加速四维流MRI采集用于腹部血管流量量化的可行性，并将其图像质量、流量量化和观察者间的可重复性与标准呼吸导航门控四维流MRI采集进行比较。10例疑似门静脉高压症的前瞻性患者（男/女：7/3，平均年龄= 58岁）接受了两次4D血流MRI成像。k−t加速采集比标准呼吸触发采集快约3倍（3:11 min±0:12 min/9:17 min±1:41 min, p < 0.001）。采办单位和观察员之间的船舶识别协议是实质性的。门静脉和主动脉的平均血流序列间一致性较好（CV < 15%），肝动脉和脾动脉的一致性较差（CV = 11-38%）。k−t加速采集记录了小动脉流速降低和脾静脉流量减少。呼吸门控与增加的加速度和空间分辨率相结合，以改善这些血管的流量测量。
Volumetric phase-contrast magnetic resonance imaging with three-dimensional velocity encoding (4D flow MRI) has shown utility as a non-invasive tool to examine altered blood flow in chronic liver disease. Novel 4D flow MRI pulse sequences with spatio-temporal acceleration can mitigate the long acquisition times of standard 4D flow MRI, which are an impediment to clinical adoption. The purpose of our study was to demonstrate feasibility of a free-breathing, spatio-temporal (k−t) accelerated 4D flow MRI acquisition for flow quantification in abdominal vessels and to compare its image quality, flow quantification and inter-observer reproducibility with a standard respiratory navigator-gated 4D flow MRI acquisition. Ten prospectively enrolled patients (M/F: 7/3, mean age = 58y) with suspected portal hypertension underwent both 4D flow MRI acquisitions. The k−t accelerated acquisition was approximately three times faster (3:11 min ± 0:12 min/9:17 min ± 1:41 min, p < 0.001) than the standard respiratory-triggered acquisition. Vessel identification agreement was substantial between acquisitions and observers. Average flow had substantial inter-sequence agreement in the portal vein and aorta (CV < 15%) and poorer agreement in hepatic and splenic arteries (CV = 11–38%). The k−t accelerated acquisition recorded reduced velocities in small arteries and reduced splenic vein flow. Respiratory gating combined with increased acceleration and spatial resolution are needed to improve flow measurements in these vessels.
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DOI：
10.2214/ajr.15.15995
发表时间：
2016-07
期刊：
AJR. American journal of roentgenology
影响因子：
--
作者：
Roldán-Alzate A;Francois CJ;Wieben O;Reeder SB
通讯作者：
Reeder SB
影响因子：
5.9
作者：
Frydrychowicz A;Roldan-Alzate A;Winslow E;Consigny D;Campo CA;Motosugi U;Johnson KM;Wieben O;Reeder SB
通讯作者：
Reeder SB
影响因子：
19.7
作者：
Stankovic, Zoran;Csatari, Zoltan;Markl, Michael
通讯作者：
Markl, Michael
DOI：
10.1002/jmri.26305
发表时间：
2019-04
期刊：
Journal of magnetic resonance imaging : JMRI
影响因子：
--
作者：
Bane O;Peti S;Wagner M;Hectors S;Dyvorne H;Markl M;Taouli B
通讯作者：
Taouli B
影响因子：
4.4
作者：
Frydrychowicz, A.;Landgraf, B. R.;Niespodzany, E.;Verma, R. W.;Roldan-Alzate, A.;Johnson, K. M.;Wieben, O.;Reeder, S. B.
通讯作者：
Reeder, S. B.