Four-dimensional velocity mapping of the hepatic and splanchnic vasculature with radial sampling at 3 tesla: a feasibility study in portal hypertension.
Four-dimensional velocity mapping of the hepatic and splanchnic vasculature with radial sampling at 3 tesla: a feasibility study in portal hypertension.
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DOI：
10.1002/jmri.22712
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发表时间：
2011-09
影响因子：
4.4
通讯作者：
Reeder, S. B.
中科院分区：
文献类型：
--
作者：
Frydrychowicz, A.;Landgraf, B. R.;Niespodzany, E.;Verma, R. W.;Roldan-Alzate, A.;Johnson, K. M.;Wieben, O.;Reeder, S. B.
关键词：
目的：探讨PC-VIPR成像技术在门静脉高压症患者肝脏和内脏血管显示及血流动力学分析中的可行性。24例肝硬变患者，平均年龄(55.9±10.4)岁，采用5点PC-VIPR，采用32通道体部线圈，在3T进行大体积复盖的高空间分辨率成像。血管分割和血流动力学可视化包括彩色编码的3D流线和颗粒痕迹。将分割质量与增强多时相肝脏成像进行比较。3位读者一致同意进行流型分析。计算MELD评分以评估疾病严重程度，并与图像质量相关。24例中有23例显示质量为良至优。所有的动脉血管和144/168条门静脉(PV)循环血管被明确识别。未发现与MELD评分相关。148条门静脉循环中有8条血管呈逆行(离肝)血流。尽管门静脉内有肝叶血流，但仍有3例患者存在门静脉血流的小支流。这项可行性研究证明了PC-VIPR在肝硬变和门脉高压症中同时进行肝脏和内脏血管的形态和血流动力学评估的可行性。未来的定量分析研究是有必要的。
To demonstrate the feasibility of PC-VIPR (Phase Contrast Vastly undersampled Imaging with Projection Reconstruction) for the depiction and hemodynamic analysis of hepatic and splanchnic vessels in patients with portal hypertension. 24 cirrhotic patients (55.9±10.4years) were scanned using 5-point PC-VIPR for high spatial resolution imaging with large volume coverage at 3T using a 32-channel body coil. Vessel segmentation and hemodynamic visualization included color-coded 3D streamlines and particle traces. Segmentation quality was compared to contrast-enhanced multi-phase liver imaging. Flow pattern analysis was performed in consensus of 3 readers. The MELD score was calculated to estimate disease severity and was correlated to image quality. Good to excellent visualization quality was achieved in 23/24 cases. All arterial vessels and 144/168 vessels of the portal venous (PV) circulation were unambiguously identified. No correlation with the MELD score was found. 8/148 vessels of the PV circulation demonstrated reverse (hepatofugal) flow. Hepatofugal flow small tributaries to PV flow were present in three cases despite hepatopetal flow in the PV. This feasibility study demonstrates the feasibility of PC-VIPR for simultaneous morphological and hemodynamic assessment of the hepatic and splanchnic vasculature in cirrhosis and portal hypertension. Future studies with quantitative analyses are warranted.
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影响因子：
3.3
作者：
Brau, Anja C. S.;Beatty, Philip J.;Bammer, Roland
通讯作者：
Bammer, Roland
影响因子：
13.5
作者：
Ratziu, V;Bonyhay, L;Poynard, T
通讯作者：
Poynard, T
影响因子：
4.4
作者：
Stankovic, Zoran;Frydrychowicz, Alex;Markl, Michael
通讯作者：
Markl, Michael
DOI：
10.1007/978-1-59259-885-4_4
发表时间：
2005-01-01
期刊：
PORTAL HYPERTENSION: PATHOBIOLOGY, EVALUATION, AND TREATMENT
影响因子：
--
作者：
Moreau, R;Lebrec, D
通讯作者：
Lebrec, D
影响因子：
29.4
作者：
SABBA, C;WELTIN, GG;GROSZMANN, RJ
通讯作者：
GROSZMANN, RJ