Computer therapy for the anxiety and depressive disorders is effective, acceptable and practical health care: a meta-analysis.

Computer therapy for the anxiety and depressive disorders is effective, acceptable and practical health care: a meta-analysis.
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DOI:
10.1371/journal.pone.0013196
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发表时间:
2010-10-13
期刊:
影响因子:
3.7
通讯作者:
Titov N
Titov N
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Andrews G;Cuijpers P;Craske MG;McEvoy P;Titov N

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抑郁症和焦虑症是常见的,可以用认知行为疗法(CBT)治疗,但这种疗法的使用是有限的。回顾证据表明,计算机化的CBT焦虑和抑郁症是可以接受的患者和有效的短期和长期。在符合重度抑郁症、惊恐障碍、社交恐怖症或广泛性焦虑症诊断标准的人群中,对计算机认知行为疗法与治疗或对照条件的随机对照试验进行了系统评价和数据库检索。提取了随机化数量、治疗组与对照组在主要结局指标上的优效性(Hedges g)、偏倚风险、随访时间、患者依从性和满意度。确定了22项与对照组进行比较的研究。平均效应量优效性为0.88(NNT 2.13),在所有四种疾病中获益明显。计算机化CBT的改善在中位26周的随访中得以维持。如依从性和满意度所示,可接受性良好。研究诚实性良好,偏倚风险较低。与等待列表相比,效应量无显著性高于活性治疗对照条件。五项比较计算机化CBT与传统面对面CBT的研究被确定,两种治疗模式似乎同样有益。计算机化的焦虑和抑郁症CBT,特别是通过互联网,有能力为那些可能无法得到治疗的人提供有效的可接受和实用的医疗保健。澳大利亚和新西兰临床试验注册中心ACTRN 12610000030077
Depression and anxiety disorders are common and treatable with cognitive behavior therapy (CBT), but access to this therapy is limited. Review evidence that computerized CBT for the anxiety and depressive disorders is acceptable to patients and effective in the short and longer term. Systematic reviews and data bases were searched for randomized controlled trials of computerized cognitive behavior therapy versus a treatment or control condition in people who met diagnostic criteria for major depression, panic disorder, social phobia or generalized anxiety disorder. Number randomized, superiority of treatment versus control (Hedges g) on primary outcome measure, risk of bias, length of follow up, patient adherence and satisfaction were extracted. 22 studies of comparisons with a control group were identified. The mean effect size superiority was 0.88 (NNT 2.13), and the benefit was evident across all four disorders. Improvement from computerized CBT was maintained for a median of 26 weeks follow-up. Acceptability, as indicated by adherence and satisfaction, was good. Research probity was good and bias risk low. Effect sizes were non-significantly higher in comparisons with waitlist than with active treatment control conditions. Five studies comparing computerized CBT with traditional face-to-face CBT were identified, and both modes of treatment appeared equally beneficial. Computerized CBT for anxiety and depressive disorders, especially via the internet, has the capacity to provide effective acceptable and practical health care for those who might otherwise remain untreated. Australian New Zealand Clinical Trials Registry ACTRN12610000030077
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