Polybrominated diphenyl ether serum concentrations in a Californian population of children, their parents, and older adults: an exposure assessment study.
Polybrominated diphenyl ether serum concentrations in a Californian population of children, their parents, and older adults: an exposure assessment study.
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DOI：
10.1186/s12940-015-0002-2
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发表时间：
2015-03-14
期刊：
影响因子：
--
通讯作者：
Hertz-Picciotto I
中科院分区：
文献类型：
--
作者：
Wu XM;Bennett DH;Moran RE;Sjödin A;Jones RS;Tancredi DJ;Tulve NS;Clifton MS;Colón M;Weathers W;Hertz-Picciotto I
Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in many household items. Given concerns over their potential adverse health effects, we identified predictors and evaluated temporal changes of PBDE serum concentrations. PBDE serum concentrations were measured in young children (2-8 years old; N = 67), parents of young children (<55 years old; N = 90), and older adults (≥55 years old; N = 59) in California, with concurrent floor wipe samples collected in participants’ homes in 2008-2009. We also measured serum concentrations one year later in a subset of children (N = 19) and parents (N = 42). PBDE serum concentrations in children were significantly higher than in adults. Floor wipe concentration is a significant predictor of serum BDE-47, 99, 100 and 154. Positive associations were observed between the intake frequency of canned meat and serum concentrations of BDE-47, 99 and 154, between canned meat entrees and BDE-154 and 209, as well as between tuna and white fish and BDE-153. The model with the floor wipe concentration and food intake frequencies explained up to 40% of the mean square prediction error of some congeners. Lower home values and renting (vs. owning) a home were associated with higher serum concentrations of BDE-47, 99 and 100. Serum concentrations measured one year apart were strongly correlated as expected (r = 0.70-0.97) with a slight decreasing trend. Floor wipe concentration, food intake frequency, and housing characteristics can explain 12-40% of the prediction error of PBDE serum concentrations. Decreasing temporal trends should be considered when characterizing long-term exposure. The online version of this article (doi:10.1186/s12940-015-0002-2) contains supplementary material, which is available to authorized users.
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影响因子：
10.4
作者：
Herbstman JB;Sjödin A;Kurzon M;Lederman SA;Jones RS;Rauh V;Needham LL;Tang D;Niedzwiecki M;Wang RY;Perera F
通讯作者：
Perera F
影响因子：
11.4
作者：
Johnson, Paula I.;Stapleton, Heather M.;Slodin, Andreas;Meeker, John D.
通讯作者：
Meeker, John D.
影响因子：
6
作者：
Hertz-Picciotto, Irva;Cassady, Diana;Vogt, Raea
通讯作者：
Vogt, Raea
影响因子：
11.4
作者：
Rose M;Bennett DH;Bergman A;Fängström B;Pessah IN;Hertz-Picciotto I
通讯作者：
Hertz-Picciotto I
影响因子：
11.4
作者：
Harrad, S;Wijesekera, R;Baker, R
通讯作者：
Baker, R