Anodal transcranial direct current stimulation over the posterior parietal cortex reduces the onset time to the rubber hand illusion and increases the body ownership
Anodal transcranial direct current stimulation over the posterior parietal cortex reduces the onset time to the rubber hand illusion and increases the body ownership
复制标题
后顶叶皮质的阳极经颅直流电刺激减少了橡胶手错觉的发生时间并增加了身体所有权
DOI：
10.1007/s00221-018-5353-9
复制
发表时间：
2018
影响因子：
2
通讯作者：
P. Boggio
中科院分区：
文献类型：
--
作者：
Marilia Lira;Fernanda Naomi Pantaleão;Carolina Gudin de Souza Ramos;P. Boggio
橡胶手错觉（RHI）诱导的身体所有权与一个涉及额-顶叶回路的神经网络有关。先前的功能性神经影像学研究已经证明，顶叶区的神经激活与多感觉整合处理和身体感觉位置的重新校准有关，而腹侧运动前皮层的激活与RHI期间的身体自我归因有关。我们的研究旨在探讨经颅直流电刺激（tDCS）对RHI期间后顶叶皮层（PPC）或运动前皮层（PMv）的影响，以解决这两个大脑区域在幻觉中的具体作用。156名年轻成人（年龄21.2±3.13岁，均为右撇子）被纳入受试者间设计实验。参与者分别在右侧PPC或右侧PMv上接受了阳极、阴极和假tDCS，并以同步或异步的方式体验了刷触橡胶手和自己左手的视觉触觉刺激。RHI通过(1)橡胶手身体所有权感的开始时间，(2)本体感觉漂移，以及(3)参与者报告的幻觉强度问卷来量化。在同步条件下，所有受试者都感受到了RHI。然而，我们发现错觉的开始时间可以被PPC上的阳极tDCS条件所调节：阳极tDCS减少了错觉的开始时间和身体所有权的主观体验。这些发现表明，顶叶区域在RHI中视觉和触觉多感觉整合的速度中起着至关重要的作用，并介绍了tDCS作为一种技术，可以加快人工身体部位整合的时间，增加身体所有权的感知。
The body ownership induced by the rubber hand illusion (RHI) has been related to a neural network involving a frontal–parietal circuit. Previous functional neuroimaging studies have demonstrated neural activation in the parietal area relative to the multisensory integration processing and to the recalibration of the felt position of body while a ventral premotor cortex activation has been linked to bodily self-attribution during the RHI. Our study aimed to investigate the effects of transcranial direct current stimulation (tDCS) on the posterior parietal cortex (PPC) or on the premotor cortex (PMv) during RHI to address the specific roles of these two brain areas in the illusion. 156 young adult participants (21.2 ± 3.13 years old; all right-handed) were enrolled for this between-subjects design experiment. Participants received anodal, cathodal and sham tDCS in three different sessions on the right PPC or right PMv and experienced visual–tactile stimulation from the brushes touching the rubber hand and their own left hand in synchronous or asynchronous manner. The RHI was quantified by the (1) onset time for the feeling of body ownership of the rubber hand, (2) proprioceptive drift, and (3) questionnaire about the intensity of the illusion as reported by the participant. All subjects felt the RHI during the synchronous condition. However, we found that the illusion onset time can be modulated by the anodal tDCS condition on the PPC: anodal tDCS decreased the illusion onset time and the subjective experience of body ownership. These findings suggest that the parietal area plays a crucial role in the speed of visual and tactile multisensory integration in the RHI and introduce tDCS as technique that can accelerate the time to integrate an artificial body part and increased the perception of body ownership.
影响因子：
4.8
作者：
Limanowski, Jakub;Blankenburg, Felix
通讯作者：
Blankenburg, Felix
DOI：
10.1017/s1461145707007833
发表时间：
2008-03-01
影响因子：
4.8
作者：
Boggio, Paulo S.;Rigonatti, Sergio P.;Fregni, Felipe
通讯作者：
Fregni, Felipe