Sample interval modulation for the simultaneous acquisition of displacement vector data in magnetic resonance elastography: theory and application.

Sample interval modulation for the simultaneous acquisition of displacement vector data in magnetic resonance elastography: theory and application.
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DOI:
10.1088/0031-9155/58/24/8663
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发表时间:
2013-12-21
影响因子:
3.5
通讯作者:
Magin RL
Magin RL
中科院分区:
工程技术2区
文献类型:
--
作者:
Klatt D;Yasar TK;Royston TJ;Magin RL

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SampLe Interval Modulation -magnetic resonance elastography (SLIM-MRE) is introduced for simultaneously encoding all three displacement projections of a monofrequency vibration into the MR signal phase. In SLIM-MRE, the individual displacement components are observed using different sample intervals. In doing so, the components are modulated with different apparent frequencies in the MR signal phase expressed as a harmonic function of the start time of the motion encoding gradients and can thus be decomposed by applying a Fourier transform to the sampled multidirectional MR phases. In this work, the theoretical foundations of SLIM-MRE are presented and the new idea is implemented using a high field (11.7 T) vertical bore magnetic resonance imaging system on an inhomogeneous agarose gel phantom sample. The local frequency estimation-derived stiffness values were the same within the error margins for both the new SLIM-MRE method and for conventional MRE, while the number of temporally-resolved MRE experiments needed for each study was reduced from three to one. In this work, we present for the first time, monofrequency displacement data along three sensitization directions that were acquired simultaneously and stored in the same k-space.
通过磁共振弹性成像确定阿尔茨海默氏病的大脑硬度降低。
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