Development and characterization of a tissue mimicking psyllium husk gelatin phantom for ultrasound and magnetic resonance imaging.
Development and characterization of a tissue mimicking psyllium husk gelatin phantom for ultrasound and magnetic resonance imaging.
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模拟胸骨果皮明胶幻影的组织的开发和表征，用于超声和磁共振成像。
DOI：
10.1080/02656736.2020.1739345
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Parker DL
中科院分区：
文献类型：
--
作者：
Hofstetter LW;Fausett L;Mueller A;Odéen H;Payne A;Christensen DA;Parker DL
旨在开发和表征组织模拟体模，该体模能够直接比较用于监测高强度聚焦超声（HIFU）治疗的磁共振（MR）和超声（US）成像技术。在没有添加物的情况下，明胶体模几乎不产生US成像所需的任何散射。本研究将MR和US图像特征表征为车前子壳浓度的函数，加入车前子壳浓度以增加US散射。用不同浓度的车前子壳构建明胶模型。在9种不同浓度下评价了车前子壳浓度对US B型和MR成像的影响。采集T1、T2和T2* MR图。声学特性（衰减和声速），测量频率为0.6，1.0，1.8，和3.0 MHz的通过传输技术。体模弹性性能的时间和温度依赖性进行了评价。超声图像的回声随着车前子壳浓度的增加而增加，而梯度回波MR图像的质量随着浓度的增加而降低。对于所有幻影，测量的声速范围在1567-1569 m/s之间，衰减范围在0.42-0.44 dB/（cm × MHz）之间。测量的T1范围为974-1038 ms。T2和T2* 值范围分别为97-108 ms和49-89 ms，两者均显示出随车前子壳浓度增加而降低的趋势。使用美国剪切波速度测量法测量的体模刚度随年龄增加而增加，随温度升高而降低。所提出的两用仿组织体模易于制造，并可用于比较和评估US引导和MR引导的HIFU成像协议。
To develop and characterize a tissue-mimicking phantom that enables the direct comparison of magnetic resonance (MR) and ultrasound (US) imaging techniques useful for monitoring high-intensity focused ultrasound (HIFU) treatments. With no additions, gelatin phantoms produce little if any scattering required for US imaging. This study characterizes the MR and US image characteristics as a function of psyllium husk concentration, which was added to increase US scattering. Gelatin phantoms were constructed with varying concentrations of psyllium husk. The effects of psyllium husk concentration on US B-mode and MR imaging were evaluated at nine different concentrations. T1, T2, and T2* MR maps were acquired. Acoustic properties (attenuation and speed of sound) were measured at frequencies of 0.6, 1.0, 1.8, and 3.0 MHz using a through-transmission technique. Phantom elastic properties were evaluated for both time and temperature dependence. Ultrasound image echogenicity increased with increasing psyllium husk concentration while quality of gradient-recalled echo MR images decreased with increasing concentration. For all phantoms, the measured speed of sound ranged between 1567–1569 m/s and the attenuation ranged between 0.42–0.44 dB/(cm∙MHz). Measured T1 ranged from 974–1038 ms. The T2 and T2* values ranged from 97–108 ms and 49–89 ms, respectively, with both showing a decreasing trend with increased psyllium husk concentration. Phantom stiffness, measured using US shear-wave speed measurements, increased with age and decreased with increasing temperature. The presented dual-use tissue-mimicking phantom is easy to manufacture and can be used to compare and evaluate US-guided and MR-guided HIFU imaging protocols.
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DOI：
10.1186/s40349-015-0030-y
发表时间：
2015
期刊：
Journal of therapeutic ultrasound
影响因子：
--
作者：
Farrer AI;Odéen H;de Bever J;Coats B;Parker DL;Payne A;Christensen DA
通讯作者：
Christensen DA
DOI：
10.3109/02656736.2015.1009180
发表时间：
2015-03
期刊：
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
影响因子：
--
作者：
Lewis MA;Staruch RM;Chopra R
通讯作者：
Chopra R
影响因子：
3.3
作者：
de Bever, Joshua T.;Odeen, Henrik;Parker, Dennis L.
通讯作者：
Parker, Dennis L.
DOI：
10.1109/tuffc.2011.1959
发表时间：
2011-07-01
影响因子：
3.6
作者：
King, Randy L.;Liu, Yunbo;Harris, Gerald R.
通讯作者：
Harris, Gerald R.
影响因子：
3.8
作者：
MADSEN, EL;ZAGZEBSKI, JA;FRANK, GR
通讯作者：
FRANK, GR