Affect variability and inflammatory markers in midlife adults.
Affect variability and inflammatory markers in midlife adults.
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DOI：
10.1037/hea0000868
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发表时间：
2020-08
期刊：
影响因子：
--
通讯作者：
Graham-Engeland JE
中科院分区：
文献类型：
--
作者：
Jones DR;Smyth JM;Engeland CG;Sliwinski MJ;Russell MA;Sin NL;Almeida DM;Graham-Engeland JE
较高的影响变异性（个体随时间变化的影响程度）与较差的健康指标有关，但与炎症的关系尚不清楚。本研究的目的是检验情绪变异性是否以与稳定性理论或脆弱的积极情绪理论一致的方式与炎症有关，以及这种联系是线性的还是非线性的。在一个种族多样化的样本中（N=231，年龄在25-65岁之间，65%为女性，62%为黑人，25%为西班牙裔），我们检查了积极影响（PA）和消极影响（NA）可变性是否与循环炎症因子（一种由IL-1β、IL-4、IL-6、IL-8、IL-10、TNF-α、IFN-γ）和c反应蛋白（CRP）呈线性或二次相关性，以及个人平均影响是否缓和了这些相关性。使用生态瞬时评估（EMA）对情感状态进行评估，每天5次，持续两周，在EMA期结束时抽血。个体标准偏差（iSD）的情感状态指数的影响变异性。二次关联表明中度NA变异性与较低的CRP相关。有证据表明，仅与PA存在显著的线性相关性：对于那些具有较高人均PA的患者，PA变异性与细胞因子组合呈正相关。人平均PA和人平均NA都调节了二次关联，因此对于那些具有高平均影响的人来说，高和低影响变异性都与全身性炎症有关。结果与脆弱情感理论一致，表明情感变异性与健康指标之间的关联可能因个人平均情感而异。
Higher affect variability (the extent to which individuals vary in their affect over time) has been associated with poorer health indicators, but associations with inflammation are less well understood. The purpose of the present study was to examine whether affect variability was associated with inflammation in ways consistent with the stability theory or the fragile positive affect theory, and whether associations were linear or non-linear. In a racially diverse sample (N=231; aged 25–65; 65% female; 62% Black; 25% Hispanic), we examined whether positive affect (PA) and negative affect (NA) variability exhibited linear or quadratic associations with circulating inflammatory cytokines (a composite measure comprised of IL-1β, IL-4, IL-6, IL-8, IL-10, TNF-α, IFN-γ), and C-reactive protein (CRP) and whether person-mean affect moderated these associations. Affective states were assessed using ecological momentary assessments (EMA) five times per day for two weeks, with a blood draw at the end of the EMA period. Individual standard deviations (iSD) of affective states indexed affect variability. A quadratic association indicated that moderate NA variability was associated with lower CRP. There was evidence of significant moderation by linear associations with PA only: For those with higher person-mean PA, PA variability was positively associated with the cytokine composite. Both person-mean PA and person-mean NA moderated quadratic associations, such that for those with high person-mean affect, both high and low affect variability was associated with systemic inflammation. Results are in line with fragile affect theory suggesting that associations between affect variability and health indicators may vary by person-mean affect.
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影响因子：
3.3
作者：
Dorn LD;Gayles JG;Engeland CG;Houts R;Cizza G;Denson LA
通讯作者：
Denson LA
影响因子：
15.1
作者：
Out, Dorothee;Hall, Rosalie J.;Granger, Douglas A.;Page, Gayle G.;Woods, Stephanie J.
通讯作者：
Woods, Stephanie J.
影响因子：
4.2
作者：
Gruber, June;Kogan, Aleksandr;Mauss, Iris B.
通讯作者：
Mauss, Iris B.
DOI：
10.1037/emo0000343
发表时间：
2018-03
期刊：
Emotion (Washington, D.C.)
影响因子：
--
作者：
Ong AD;Benson L;Zautra AJ;Ram N
通讯作者：
Ram N
影响因子：
3.7
作者：
Pripp AH;Stanišić M
通讯作者：
Stanišić M