Novel origins of lineage founder cells in the direct-developing sea urchin Heliocidaris erythrogramma.
Novel origins of lineage founder cells in the direct-developing sea urchin Heliocidaris erythrogramma.
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直接发育的海胆Heliocidaris erythrogramma中谱系创始细胞的新起源。
DOI：
10.1016/0012-1606(90)90100-w
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发表时间：
1990
影响因子：
2.7
通讯作者：
Raff,RA
中科院分区：
文献类型：
--
作者：
Wray,GA;Raff,RA
通过显微注射四甲基罗丹明-葡聚糖，追踪了直接发育的海胆 Heliocidaris erythrogramma 32 细胞胚胎中每个卵裂球的谱系和命运。结果揭示了间接海胆发育的祖先细胞谱系模式的实质性进化改变。这些修改中最重要的是细胞谱系分离的时间和顺序的变化：植物外胚层创始细胞始终比间接发育过程中出现得早，而内部创始细胞通常分离较晚且以不同的顺序。胚胎的比例也发生了改变，注定会成为各种细胞类型和幼虫结构。外胚层，特别是前庭外胚层，在 H 细胞总体积中占较大比例。红细胞病。在内部细胞类型中，与间接海胆发育过程相比，体腔消耗的剩余细胞体积较多，而内胚层消耗的剩余细胞体积较少。进化修饰在 H 幼虫细胞类型和结构的位置起源中也很明显。红细胞病。这些包括预期细胞命运轴相对于由裂解平面定义的动植物轴的明显倾斜。 H 细胞谱系中的这些进化变化一起。相对于间接发育，红眼病导致细胞命运背腹对称性加速丧失。其细胞谱系中重排的程度和多样性表明H.红眼虫是一种经过高度改造的新颖形式，而不是退化的黄线虫幼虫。这些相同的修饰强调了海胆发育中细胞谱系、基因表达和幼虫形态之间的进化灵活关系。
The lineage and fate of each blastomere in the 32-cell embryo of the direct-developing sea urchinHeliocidaris erythrogrammahave been traced by microinjection of tetramethylrhodamine-dextran. The results reveal substantive evolutionary modifications of the ancestral cell lineage pattern of indirect sea urchin development. Significant among these modifications are changes in the time and order of cell lineage segregation: vegetal ectodermal founder cells consistently arise earlier than during indirect development, while internal founder cells generally segregate later and in a different sequence. Modifications have also arisen in proportions of the embryo fated to become various cell types and larval structures. Ectodermal fates, particularly vestibular ectoderm, comprise a greater proportion of the total cellular volume inH. erythrogramma. Among internal cell types, coelom consumes more and endoderm less of the remaining cellular volume than during indirect sea urchin development. Evolutionary modifications are also apparent in the positional origin of larval cell types and structures inH. erythrogramma. These include an apparent tilt in the axis of prospective cell fate relative to the animal-vegetal axis as defined by cleavage planes. Together these evolutionary changes in the cell lineage ofH. erythrogrammaproduce an accelerated loss of dorsoventral symmetry in cell fate relative to indirect development. The extent and diversity of rearrangements in its cell lineage indicate that the nonfeeding larva ofH. erythrogrammais a highly modified, novel form rather than a degenerate pluteus larva. These same modifications underscore the evolutionarily flexible relationship between cell lineage, gene expression, and larval morphology in sea urchin development.
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关于澳大利亚海胆 Toxocidaris erythrogrammus 显着且缩短的发育的初步说明
影响因子：
4.6
作者：
T. Mortensen
通讯作者：
T. Mortensen
DOI：
--
发表时间：
--
期刊：
影响因子：
--
作者：
F. R. Lillie
通讯作者：
F. R. Lillie
线虫 Panagrellus redivivus 的胚胎后非性腺细胞谱系：描述以及与秀丽隐杆线虫的比较。
影响因子：
2.7
作者：
Sternberg,PW;Horvitz,HR
通讯作者：
Horvitz,HR
DOI：
10.1017/cbo9780511612961.013
发表时间：
2001-08
期刊：
--
影响因子：
--
作者：
J. Levinton
通讯作者：
J. Levinton
影响因子：
3.3
作者：
J. Hedgpeth
通讯作者：
J. Hedgpeth