Postembryonic nongonadal cell lineages of the nematode Panagrellus redivivus: description and comparison with those of Caenorhabditis elegans.
Postembryonic nongonadal cell lineages of the nematode Panagrellus redivivus: description and comparison with those of Caenorhabditis elegans.
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线虫 Panagrellus redivivus 的胚胎后非性腺细胞谱系：描述以及与秀丽隐杆线虫的比较。
DOI：
10.1016/0012-1606(82)90251-2
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发表时间：
1982
影响因子：
2.7
通讯作者：
Horvitz,HR
中科院分区：
文献类型：
--
作者：
Sternberg,PW;Horvitz,HR
本文描述了线虫Panagrellus redivus的胚后非性腺细胞谱系，并与秀丽隐杆线虫的非性腺细胞谱系进行了比较。初孵幼虫的形态特征为：再分雌、雄和C. eleganshermaphrodites和男性非常相似。一组几乎完全相同的胚细胞在胚后分裂。重新划分和C.在神经、肌肉、皮下和消化系统中产生类似的变化。大多数这些细胞谱系是不变的，但是，有相当大的变化，在细胞分裂的数量在相对广泛的谱系的外侧皮下组织ofP。重新划分。通常，InP。再分裂雌性，55个原始细胞产生635个存活后代，29个细胞死亡;在再分裂的雄性中，59个母细胞产生758个存活后代和35个细胞死亡。产生雄性尾细胞的谱系。重新划分和C.优雅几乎是相同的;因此，这些结构的显著不同的特征一定反映了谱系历史中等同细胞的形态发生的差异。激光消融实验表明，性腺诱导外阴发育和细胞间的相互作用是重要的，在指定的命运下皮前体细胞。侧皮下谱系提供了明显的复杂谱系从模块化亚谱系的建设引人注目的例子;一个简单的模式的细胞分裂和细胞命运发生70次在P。重新划分女性。在细胞谱系上，P.重新划分和C. elegans是相对较小的，许多似乎涉及两种类型的进化变化：亚系的替代，和修改的亚系的四类血统转换先前提出的基础上比较ofP。重新划分和C. elegansgonadal细胞谱系（斯滕贝格和Horvitz，1981）。这些类型的差异表明，细胞谱系的遗传编程包括指定何时何地使用特定亚谱系的指令，以及指定该亚谱系性质的其他指令。
The postembryonic nongonadal cell lineages of the nematodePanagrellus redivivusare described and compared with those ofCaenorhabditis elegans. The newly hatched larvae ofP. redivivusfemales and males andC. eleganshermaphrodites and males are very similar. An almost identical set of blast cells divides postembryonically inP. redivivusandC. elegansto produce similar changes in the neuronal, muscular, hypodermal, and digestive systems. Most of these cell lineages are invariant; however, there is substantial variability in the number of cell divisions in the relatively extensive lineages of the lateral hypodermis ofP. redivivus. Typically, inP. redivivusfemales, 55 blast cells generate 635 surviving progeny and 29 cell deaths; inP. redivivusmales, 59 blast cells generate 758 surviving progeny and 35 cell deaths. The lineages generating the cells of the male tails ofP. redivivusandC. elegansare almost identical; thus, the grossly different characteristics of these structures must reflect differences in the morphogenesis of cells equivalent in lineage history. Laser ablation experiments demonstrate that the gonad induces vulva development and that cell-cell interactions are important in specifying the fates of hypodermal precursor cells. The lateral hypodermal lineages provide striking examples of the apparent construction of complex lineages from modular sublineages; one simple pattern of cell divisions and cell fates occurs 70 times in theP. redivivusfemale. The differences in cell lineage betweenP. redivivusandC. elegansare relatively minor, and many appear to have involved two types of evolutionary change: the replacement of sublineages, and the modification of sublineages by the four classes of lineage transformations previously proposed based on a comparison ofP. redivivusandC. elegansgonadal cell lineages (Sternberg and Horvitz, 1981). These types of differences suggest that the genetic programming of cell lineage includes instructions specifying where and when a particular sublineage is utilized, and other instructions specifying the nature of that sublineage.
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影响因子：
3.3
作者：
H. Horvitz;J. Sulston
通讯作者：
H. Horvitz;J. Sulston
影响因子：
2
作者：
J. Lewis;L. Wolpert
通讯作者：
L. Wolpert
影响因子：
2.5
作者：
SULSTON, J;DEW, M;BRENNER, S
通讯作者：
BRENNER, S
蝗虫克隆和巢中的神经元重复和缺失。
影响因子：
56.9
作者：
C. Goodman
通讯作者：
C. Goodman
DOI：
10.1073/pnas.75.1.376
发表时间：
1978-01-01
影响因子：
11.1
作者：
DEPPE, U;SCHIERENBERG, E;VONEHRENSTEIN, G
通讯作者：
VONEHRENSTEIN, G