Concurrent TMS-fMRI reveals dynamic interhemispheric influences of the right parietal cortex during exogenously cued visuospatial attention.
Concurrent TMS-fMRI reveals dynamic interhemispheric influences of the right parietal cortex during exogenously cued visuospatial attention.
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DOI:
10.1111/j.1460-9568.2010.07580.x
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发表时间:
2011-03
期刊:
影响因子:
--
通讯作者:
Chambers CD
中科院分区:
文献类型:
--
作者:
Heinen K;Ruff CC;Bjoertomt O;Schenkluhn B;Bestmann S;Blankenburg F;Driver J;Chambers CD
We used concurrent transcranial magnetic stimulation and functional MRI (TMS-fMRI) during a visuospatial cueing paradigm in humans, to study the causal role of the right angular gyrus (AG) as a source of attentional control. Our findings show that TMS over the right AG (high vs. low intensity) modulates neural responses interhemispherically, in a manner that varies dynamically with the current attentional condition. The behavioural impact of such TMS depended not only on the target hemifield but also on exogenous cue validity, facilitating spatial reorienting to invalidly cued right visual targets. On a neural level, right AG TMS had corresponding interhemispheric effects in the left AG and left retinotopic cortex, including area V1. We conclude that the direction of covert visuospatial attention can involve dynamic interplay between the right AG and remote interconnected regions of the opposite left hemisphere, whereas our findings also suggest that the right AG can influence responses in the retinotopic visual cortex.
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影响因子:
10.6
作者:
Bohning, DE;Shastri, A;George, MS
通讯作者:
George, MS
DOI:
10.1523/jneurosci.3043-08.2008
发表时间:
2008-12-03
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
Blankenburg F;Ruff CC;Bestmann S;Bjoertomt O;Eshel N;Josephs O;Weiskopf N;Driver J
通讯作者:
Driver J
DOI:
10.1073/pnas.0905314106
发表时间:
2009-11-24
影响因子:
11.1
作者:
Margulies, Daniel S.;Vincent, Justin L.;Petrides, Michael
通讯作者:
Petrides, Michael
影响因子:
1.7
作者:
Baudewig, J;Siebner, HR;Frahm, J
通讯作者:
Frahm, J
影响因子:
2.9
作者:
Chambers, Christopher D.;Stokes, Mark G.;Mattingley, Jason B.
通讯作者:
Mattingley, Jason B.