Open-Globe Injury Repairs in the American Academy of Ophthalmology IRIS® Registry 2014 - 2018: Incidence, Risk Factors, and Visual Outcomes.
Open-Globe Injury Repairs in the American Academy of Ophthalmology IRIS® Registry 2014 - 2018: Incidence, Risk Factors, and Visual Outcomes.
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美国眼科IRIS®注册表2014 - 2018年美国眼科造成的伤害维修：发病率，危险因素和视觉结果。
DOI：
10.1016/j.ophtha.2023.03.002
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发表时间：
2023-08
期刊：
影响因子：
13.7
通讯作者：
Hyman, Leslie
中科院分区：
文献类型：
--
作者：
Tomaiuolo, Maurizio;Woreta, Fasika A.;Li, Alexander;Yonekawa, Yoshihiro;Zhang, Qiang (Ed);Sharpe, James E.;Zafar, Sidra;Syed, Zeba A.;Ramesh, Sathyadeepak;Lorch, Alice C.;Hall, Nathan E.;Shah, Ankoor S.;Justin, Grant A.;Hyman, Leslie
在IRIS®注册表(Intelligence Research In Sight)中，评估需要手术修复的开放性眼球损伤的发病率和人口统计学风险因素及视力(VA)结果。回顾性队列研究。开放眼球损伤修复(OGR)患者是根据IRIS注册处2014年至2018年的当前程序术语代码(65275、65280、65285、65286、65235、65260、65265)确定的。Logistic回归模型对年龄、性别、种族、民族、美国地区、同时和后续手术以及基线退伍军人管理局进行了调整。结果包括每100,000人的年和5年发病率以及与OGR、VA和Lt；20/40以及最终随访(OGR后3至12个月)VA≤20/200相关的因素。在研究期间，总共发现了13,766例OGR，5年发病率为28.0/10万。年发病率从11.1/10万到12.7/10万不等。OGR与21岁以下(OR，1.6[95%CI：1.5-1.7])、男性与女性(OR，2.8[CI：2.7-2.9])、黑人与白人(OR，1.3[CI，1.2-1.4])、西班牙裔与非西班牙裔(OR，1.7[CI，1.6-1.8])有关；生活在南部(OR，1.4[CI，1.3-1.5])和西部(OR，1.3[CI，1.2-1.4])(VS中西部)地区，与亚裔和白人呈负相关(OR，0.6[CI，0.6-0.7])。对2966名在受伤前和随访时进行VA观察的患者的VA结果进行了分析。最终随访时视力损害(VA<；20/40)与出现时的VA≤20/200有关(20/200比20/40-OR，11.1[CI，8.0-15.7])；年龄较大，例如80岁以上(与21岁相比)(OR，5.8[CI，3.2-10.7])；黑人(与白人)(OR，1.8[CI，1.3-2.6])。OGR后VA≤20/200时的危险因素相似。在1,063名视力为20/200或更差的OGR患者中，35%(1,063/2,996)的患者在随访时视力没有改善到20/200以上。我们的发现揭示了OGR风险的种族差异和值得进一步探索的糟糕的视觉结果。
To estimate incidence and evaluate demographic risk factors and visual acuity (VA) outcomes of open globe injuries requiring surgical repair in the IRIS® Registry (Intelligent Research in Sight). Retrospective cohort study. Patients with open globe injury repairs (OGR) were identified by Current Procedural Terminology codes (65275, 65280, 65285, 65286, 65235, 65260, 65265) from 2014 to 2018 in the IRIS Registry. Logistic regression models adjusting for age, sex, race, ethnicity, US region, concurrent and subsequent surgeries, and baseline VA. Outcomes included annual and 5-year incidence rates per 100,000 persons and factors associated with OGR, VA < 20/40, and VA ≤ 20/200 at final follow up (3 to 12 months post OGR). A total of 13,766 OGR’s were identified during the study period, and 5-year incidence was 28.0/100,000. Annual incidence ranged from 11.1 to 12.7/100,000. OGR was associated with ages 21–40 years (yrs) compared to younger than 21 yrs (OR, 1.6 [95% CI: 1.5–1.7]); males compared to females (OR, 2.8 [CI: 2.7–2.9]); Black vs. White race (OR, 1.3 [CI, 1.2–1.4]); Hispanic vs. Non-Hispanic ethnicity (OR, 1.7 [CI, 1.6–1.8]); living in the South (OR, 1.4 [CI, 1.3–1.5]) and West (OR, 1.3 [CI, 1.2–1.4]) (vs Midwest) regions and inversely associated with Asian vs. White race (OR, 0.6 [CI, 0.6–0.7]). VA outcomes were analyzed in a subset of 2,966 patients with VA observations before the injury and at follow-up. Vision impairment (VA < 20/40) at final follow up was associated with VA ≤ 20/200 at presentation (20/200 better than 20/40 - OR, 11.1 [CI, 8.0–15.7]); older age e.g. 80+ yrs (vs < 21 yrs) (OR, 5.8 [CI, 3.2–10.7]); and Black race (vs White) (OR, 1.8 [CI, 1.3–2.6]). Risk factors were similar for VA ≤ 20/200 post OGR. Among the 1,063 OGR patients presenting with VA 20/200 or worse, VA did not improve to better than 20/200 at follow up in 35% (1,063/2,996) of patients. Our findings bring to light racial disparities in risk of OGR and poor visual outcomes that warrant further exploration.
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影响因子：
158.5
作者：
SOMMER, A;TIELSCH, JM;EZRINE, S
通讯作者：
EZRINE, S
影响因子：
--
作者：
KLOPFER, J;TIELSCH, JM;CANNER, JK
通讯作者：
CANNER, JK
影响因子：
13.7
作者：
Chiang, Michael F.;Sommer, Alfred;Parke, David W., II
通讯作者：
Parke, David W., II
影响因子：
--
作者：
Parke, D. W., II;Lum, F.;Rich, W. L.
通讯作者：
Rich, W. L.
影响因子：
4.1
作者：
Desai, P;MacEwen, CJ;Minassian, DC
通讯作者：
Minassian, DC