Laser induced breakdown spectroscopy for the rapid detection of SARS-CoV-2 immune response in plasma.
Laser induced breakdown spectroscopy for the rapid detection of SARS-CoV-2 immune response in plasma.
复制标题
激光诱导击穿光谱用于血浆中SARS-CoV-2免疫应答的快速检测
DOI：
10.1038/s41598-022-05509-z
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发表时间：
2022-01-31
影响因子：
4.6
通讯作者：
Melikechi N
中科院分区：
文献类型：
--
作者：
Berlo K;Xia W;Zwillich F;Gibbons E;Gaudiuso R;Ewusi-Annan E;Chiklis GR;Melikechi N
As the SARS-CoV-2 pandemic persists, methods that can quickly and reliably confirm infection and immune status is extremely urgently and critically needed. In this contribution we show that combining laser induced breakdown spectroscopy (LIBS) with machine learning can distinguish plasma of donors who previously tested positive for SARS-CoV-2 by RT-PCR from those who did not, with up to 95% accuracy. The samples were also analyzed by LIBS-ICP-MS in tandem mode, implicating a depletion of Zn and Ba in samples of SARS-CoV-2 positive subjects that inversely correlate with CN lines in the LIBS spectra.
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DOI：
10.1016/j.fct.2021.112161
发表时间：
2021-06
期刊：
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
影响因子：
--
作者：
Domingo JL;Marquès M
通讯作者：
Marquès M
影响因子：
13.8
作者：
Angulo FJ;Finelli L;Swerdlow DL
通讯作者：
Swerdlow DL
影响因子：
4
作者：
Multari, R. A.;Cremers, D. A.;Duncan, R.
通讯作者：
Duncan, R.
影响因子：
3.4
作者：
Paton, Chad;Hellstrom, John;Hergt, Janet
通讯作者：
Hergt, Janet
影响因子：
--
作者：
Rehse, S. J.;Salimnia, H.;Miziolek, A. W.
通讯作者：
Miziolek, A. W.