The effects of some essential and toxic metals/metalloids in COVID-19: A review.

The effects of some essential and toxic metals/metalloids in COVID-19: A review.
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一些必需和有毒金属/类金属在COVID-19中的作用:综述。

DOI:
10.1016/j.fct.2021.112161
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发表时间:
2021-06
期刊:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
影响因子:
--
通讯作者:
Marquès M
Marquès M
中科院分区:
其他
文献类型:
--
作者:
Domingo JL;Marquès M

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为了深入了解新型冠状病毒SARS-CoV-2的特征,其传染性和传播方式,特别是与COVID-19的临床和严重程度以及潜在治疗有关的一切,已经进行了数千项研究。从这个意义上说,必需金属和有毒金属/类金属在这种疾病的发展和过程中的作用正在研究中。金属/类金属,如砷、镉、铅、汞或钒,是已知对哺乳动物有毒性作用的元素,而钴、铜、铁、锰、硒和锌等微量元素被认为是必不可少的。鉴于金属/类金属在营养和人类健康中的重要性,本综述旨在评估各种必需和有毒金属/类金属与COVID-19相关健康结果之间的关系。我们可以得出结论,必须特别关注COVID-19患者体内必需微量元素的负荷/水平,主要是锌和硒。另一方面,应尽量避免接触一般的空气污染物,特别是有毒金属/类金属,以减少病毒感染的可能性,包括SARS-CoV-2。
Thousands of studies have been conducted in order to understand in depth the characteristics of the novel coronavirus SARS-CoV-2, its infectivity and ways of transmission, and very especially everything related to the clinical and severity of the COVID-19, as well as the potential treatments. In this sense, the role that essential and toxic metals/metalloids have in the development and course of this disease is being studied. Metals/metalloids such as arsenic, cadmium, lead, mercury or vanadium, are elements with known toxic effects in mammals, while trace elements such as cobalt, copper, iron, manganese, selenium and zinc are considered essential. Given the importance of metals/metalloids in nutrition and human health, the present review was aimed at assessing the relationship between various essential and toxic metals/metalloids and the health outcomes related with the COVID-19. We are in the position to conclude that particular attention must be paid to the load/levels of essential trace elements in COVID-19 patients, mainly zinc and selenium. On the other hand, the exposure to air pollutants in general, and toxic metal/metalloids in particular, should be avoided as much as possible to reduce the possibilities of viral infections, including SARS-CoV-2.
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发表时间: 2016-04
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