Cochlear Micromechanics and Macromechanics
Cochlear Micromechanics and Macromechanics
复制标题
耳蜗微观力学和宏观力学
DOI：
10.1007/978-1-4612-0757-3_4
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发表时间：
1996
影响因子：
6.4
通讯作者：
R. Patuzzi
中科院分区：
文献类型：
--
作者：
R. Patuzzi
哺乳动物耳蜗的主要任务是分析声音的强度、时间和频率。为了实现这一目标，空气中的声音通过中耳与耳蜗内密度较大的水介质“匹配”，有效地在耳蜗液中产生压力波动，并使带状基底膜（BM）和位于其上的Corti感觉器官（OC）产生振动。耳蜗隔（BM和OC）的振动通常以波或波纹的形式从镫骨向耳蜗尖传播（见图1.5,Dallos，第1章）。对于纯音刺激，声波在传播过程中不断增长，在一个被称为声波特征点的位置达到最大值，然后突然崩溃，以至于在耳蜗位置（被称为声波的截止区域）之外没有振动存在。特征位和截断区沿耳蜗长度方向按位频图定位：高频靠近耳蜗基部，靠近镫骨，低频靠近耳蜗尖端。基底骨和OC相对于周围骨结构的振动被称为宏观机械振动，而OC各部分相对于彼此的复杂振动被称为微机械振动。这里值得强调的是，这两种振动通常都是原子或最多是分子的尺寸，与细胞膜的宽度相当（小于10纳米），它们不是独立的：不仅BM的宏观力学振动“驱动”OC的微观力学振动，而且微观力学极大地影响宏观力学。
The main task of the mammalian cochlea is to analyze sound in terms of its intensity, timing, and frequency content. To achieve this, sound in air is “matched” acoustically to the denser water medium within the cochlea by the middle ear, efficiently producing pressure fluctuations in the cochlear fluids and vibration of the ribbonlike basilar membrane (BM) and the sensory organ of Corti (OC) perched upon it. The vibration of the cochlear partition (BM and OC) normally takes the form of waves or ripples that travel away from the stapes and toward the cochlear apex (See Fig. 1.5, Dallos, Chapter 1). For a pure-tone stimulus, the wave grows as it travels, reaching a maximum at a position known as the wave’s characteristic place, and then collapses abruptly so that no vibration exists beyond a cochlear position known as the wave’s cutoff region. The characteristic place and cutoff region are positioned along the cochlear length according to a place-frequency map: high frequencies toward the cochlear base, closer to the stapes, and low frequencies closer to the cochlear apex. The vibration of the BM and OC relative to the surrounding bony structures is known as macromechanical vibration, while the complex vibration of the parts of the OC relative to one another is known as micromechanical vibration. It is worth stressing here that both these vibrations are normally of atomic or at most molecular dimensions, comparable with the width of a cell membrane (less than 10 nm), and they are not independent: not only does macromechanical vibration of the BM “drive” the micromechanical vibration of the OC, but the micromechanics greatly affects the macromechanics.
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DOI：
10.1073/pnas.90.18.8347
发表时间：
1993-09-15
影响因子：
11.1
作者：
EVANS, BN;DALLOS, P
通讯作者：
DALLOS, P
耳蜗微音学和听觉神经尖峰的启动：单个单元数据与从圆窗记录的神经和受体电位的相关性。
DOI：
10.1121/1.393763
发表时间：
1986
期刊：
The Journal of the Acoustical Society of America
影响因子：
--
作者：
Ruggero,MA;Robles,L;Rich,NC
通讯作者：
Rich,NC
影响因子：
2.4
作者：
NEELY, ST;KIM, DO
通讯作者：
KIM, DO
龙猫听觉神经对低频音调的反应。
DOI：
10.1121/1.389577
发表时间：
1983
期刊：
The Journal of the Acoustical Society of America
影响因子：
--
作者：
Ruggero,MA;Rich,NC
通讯作者：
Rich,NC
DOI：
10.1073/pnas.84.9.3064
发表时间：
1987-05-01
影响因子：
11.1
作者：
HOWARD, J;HUDSPETH, AJ
通讯作者：
HUDSPETH, AJ