On-line randomized controlled trial of an internet based psychologically enhanced intervention for people with hazardous alcohol consumption.
On-line randomized controlled trial of an internet based psychologically enhanced intervention for people with hazardous alcohol consumption.
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DOI：
10.1371/journal.pone.0014740
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发表时间：
2011-03-09
期刊：
影响因子：
3.7
通讯作者：
Linke S
中科院分区：
文献类型：
--
作者：
Wallace P;Murray E;McCambridge J;Khadjesari Z;White IR;Thompson SG;Kalaitzaki E;Godfrey C;Linke S
通过互联网提供的干预措施有可能以最小的增量成本解决有害酒精消费问题，并可能对公共卫生产生重大影响。据推测，与仅提供有关酒精潜在危害的信息的典型酒精网站相比，提供对心理增强的网站的访问将更大程度地减少饮酒和相关问题。 DYD-RCT 试验注册：ISRCTN 31070347。一项双臂随机对照试验完全通过 Down Your Drink (DYD) 网站在线进行。总共招募了 7935 名有害饮酒筛查呈阳性的个体，并进行了随机分组。进入试验时，报告的上周饮酒量的几何平均值为 46.0 (SD 31.2) 单位。在主要 3 个月评估点，两组的消费水平均大幅下降至 26.0 (SD 22.3) 单位。 1 个月和 12 个月时也报告了类似的变化。各组之间在 3 个月时的饮酒量（干预措施：几何平均值控制比 1.03，95% CI 0.97 至 1.10）或该结果以及任何评估的主要次要结果方面均无显着差异。填补缺失值后，结果没有发生重大变化，也没有任何证据表明干预措施的影响随着基线测量或干预措施的暴露水平而变化。研究结果并未支持以下假设：访问心理增强网站比标准做法具有额外益处，并表明需要进一步研究以优化基于互联网的行为干预措施的有效性。该试验表明，对危险饮酒人群进行基于互联网的干预措施存在广泛且潜在可持续的需求，这种干预措施可以在全球范围内提供。对照试验.com ISRCTN31070347
Interventions delivered via the Internet have the potential to address the problem of hazardous alcohol consumption at minimal incremental cost, with potentially major public health implications. It was hypothesised that providing access to a psychologically enhanced website would result in greater reductions in drinking and related problems than giving access to a typical alcohol website simply providing information on potential harms of alcohol. DYD-RCT Trial registration: ISRCTN 31070347. A two-arm randomised controlled trial was conducted entirely on-line through the Down Your Drink (DYD) website. A total of 7935 individuals who screened positive for hazardous alcohol consumption were recruited and randomized. At entry to the trial, the geometric mean reported past week alcohol consumption was 46.0 (SD 31.2) units. Consumption levels reduced substantially in both groups at the principal 3 month assessment point to an average of 26.0 (SD 22.3) units. Similar changes were reported at 1 month and 12 months. There were no significant differences between the groups for either alcohol consumption at 3 months (intervention: control ratio of geometric means 1.03, 95% CI 0.97 to 1.10) or for this outcome and the main secondary outcomes at any of the assessments. The results were not materially changed following imputation of missing values, nor was there any evidence that the impact of the intervention varied with baseline measures or level of exposure to the intervention. Findings did not provide support for the hypothesis that access to a psychologically enhanced website confers additional benefit over standard practice and indicate the need for further research to optimise the effectiveness of Internet-based behavioural interventions. The trial demonstrates a widespread and potentially sustainable demand for Internet based interventions for people with hazardous alcohol consumption, which could be delivered internationally. Controlled-Trials.com ISRCTN31070347
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