Simulation study of the second-generation MR-compatible SPECT system based on the inverted compound-eye gamma camera design.

Simulation study of the second-generation MR-compatible SPECT system based on the inverted compound-eye gamma camera design.
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DOI:
10.1088/1361-6560/aaa4fb
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发表时间:
2018-02-12
影响因子:
3.5
通讯作者:
Meng LJ
Meng LJ
中科院分区:
工程技术2区
文献类型:
--
作者:
Lai X;Meng LJ

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In this paper, we presented the simulation studies for the second-generation MRI compatible SPECT system, MRC-SPECT-II, based on an inverted compound eye (ICE) gamma camera concept. The MRC-SPECT-II system consisted of a total of 1,536 independent micro-pinhole-camera-elements (MCEs) distributed in a ring with an inner diameter of 6 cm. This system provided a FOV of 1 cm diameter and a peak geometrical efficiency of approximately 1.3% (as compared to the typical levels of 0.1%–0.01% found in modern pre-clinical SPECT instrumentations) while maintaining a sub-500 μm spatial resolution. Compared to the first-generation MRC-SPECT system (MRC-SPECT-I) developed in our lab, the MRC-SPECT-II system offered a similar resolution, but a dramatically improved sensitivity and a greatly reduced physical dimension. The latter allowed the system to be placed inside most clinical and pre-clinical MRI scanners for high-performance simultaneous MRI and SPECT imaging.
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