Cell-cell signaling during neurogenesis: some answers and many questions.
Cell-cell signaling during neurogenesis: some answers and many questions.
复制标题
神经发生过程中的细胞间信号传导:一些答案和许多问题。
DOI:
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发表时间:
1998
影响因子:
0.7
通讯作者:
Krishna Moorthi Bhat
中科院分区:
文献类型:
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作者:
Krishna Moorthi Bhat
Development of a multicellular organism requires that cells communicate with each other in order to regulate their growth, organize into tissues and coordinate their function. This cell-cell communication is mediated by signals cells receive (or send) between each other and from the environment. The signaling can be a short range remote signaling (through secreted signaling molecules), contact signaling (via plasma membrane bound molecules, gap junctions) or a long range signaling (through hormones). In this article, I have reviewed the recent advances on the role of cell-cell signaling in the development of the embryonic nervous system of the fruitfly Drosophila melanogaster and discussed some of the open questions raised by these studies. It discusses the contributions of the neurogenic genes Notch and Delta and the signaling pathways controlled by wingless, patched and hedgehog in neuroblast formation, neuroblast identity specification and neuroblast lineage elaboration.
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影响因子:
10.5
作者:
N. Patel;B. Schafer;C. Goodman;R. Holmgren
通讯作者:
N. Patel;B. Schafer;C. Goodman;R. Holmgren
影响因子:
2.7
作者:
Okamoto,H;Kuwada,JY
通讯作者:
Kuwada,JY
影响因子:
3.3
作者:
Norbert Perrimon;L. Engstrom;A. Mahowald
通讯作者:
Norbert Perrimon;L. Engstrom;A. Mahowald
影响因子:
2.7
作者:
HARTENSTEIN, V;YOUNOSSIHARTENSTEIN, A;LEKVEN, A
通讯作者:
LEKVEN, A
DOI:
10.1242/dev.114.3.815
发表时间:
1992
期刊:
Development (Cambridge, England)
影响因子:
--
作者:
Chang,S;Fan,J;Nayak,J
通讯作者:
Nayak,J