Measurement of mismatch negativity in individuals: a study using single-trial analysis.
Measurement of mismatch negativity in individuals: a study using single-trial analysis.
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DOI:
10.1111/j.1469-8986.2009.00970.x
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发表时间:
2010-07-01
期刊:
影响因子:
3.7
通讯作者:
Hardiman MJ
中科院分区:
文献类型:
--
作者:
Bishop DV;Hardiman MJ
Mismatch negativity (MMN) is measured by subtracting the averaged response to a set of standard stimuli from the averaged response to rarer deviant stimuli, and taking the amplitude of this difference wave in a given time window. This method is problematic when used to evaluate individuals, because there is no estimate of variance. We describe a new approach, in which independent components with high trial-by-trial variance are first removed. Next, each deviant response has the preceding standard response subtracted, giving a set of single trial difference waves. We illustrate this approach in analysis of MMN to brief tones in 17 adults. The best criterion for MMN combined t-test with an index of inter-trial coherence, giving significant MMN in 14 (82%) of individuals. Single-trial methods can indicate which people show MMN. However, in some clinically normal individuals there was no MMN, despite good behavioral discrimination of stimuli.
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影响因子:
2.5
作者:
McArthur, GM;Bishop, DVM
通讯作者:
Bishop, DVM
影响因子:
3.7
作者:
Yeung, Nick;Bogacz, Rafal;Cohen, Jonathan D.
通讯作者:
Cohen, Jonathan D.
DOI:
10.1016/s0168-5597(97)00024-5
发表时间:
1997-07-01
期刊:
EVOKED POTENTIALS-ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子:
--
作者:
McGee, T;Kraus, N;Nicol, T
通讯作者:
Nicol, T
影响因子:
1.6
作者:
Sinkkonen, J;Tervaniemi, M
通讯作者:
Tervaniemi, M
影响因子:
3.7
作者:
KURTZBERG, D;VAUGHAN, HG;FLIEGER, KZ
通讯作者:
FLIEGER, KZ