WOX4 and WOX14 act downstream of the PXY receptor kinase to regulate plant vascular proliferation independently of any role in vascular organisation.
WOX4 and WOX14 act downstream of the PXY receptor kinase to regulate plant vascular proliferation independently of any role in vascular organisation.
复制标题
DOI：
10.1242/dev.091314
复制
发表时间：
2013-05
期刊：
影响因子：
--
通讯作者：
Turner SR
中科院分区：
文献类型：
--
作者：
Etchells JP;Provost CM;Mishra L;Turner SR
在植物中，形成层和原形成层是维管组织的分生组织。与大多数植物细胞相比，这些组织中的干细胞很薄，而且非常长。它们特别不寻常，因为它们以高度有序的方式划分它们的长轴，平行于茎的切轴。clavat03 - like /ESR-RELATED 41 （CLE41）和PHLOEM INTERCALATED WITH XYLEM （PXY）是维管组织中调控维管细胞分裂、维管组织和木质部分化的多功能配体-受体对。一个转录因子基因，WUSCHEL HOMEOBOX RELATED 4 （WOX4）已被证明作用于PXY的下游。在这里，我们发现WOX4与WOX14在调节血管细胞分裂中起冗余作用，但这些基因在调节血管组织中没有功能。此外，我们发现PXY和受体激酶ERECTA （ER）之间的相互作用会影响维管组织的组织，但不会影响细胞分裂的速度，这表明细胞分裂和维管组织在基因上是可分离的。我们的观察结果也支持一个模型，即组织组织和细胞分裂是通过PXY和ER信号整合的，它们共同协调不同细胞类型的发育，这对正常的干细胞形成至关重要。
In plants, the cambium and procambium are meristems from which vascular tissue is derived. In contrast to most plant cells, stem cells within these tissues are thin and extremely long. They are particularly unusual as they divide down their long axis in a highly ordered manner, parallel to the tangential axis of the stem. CLAVATA3-LIKE/ESR-RELATED 41 (CLE41) and PHLOEM INTERCALATED WITH XYLEM (PXY) are a multifunctional ligand-receptor pair that regulate vascular cell division, vascular organisation and xylem differentiation in vascular tissue. A transcription factor gene, WUSCHEL HOMEOBOX RELATED 4 (WOX4) has been shown to act downstream of PXY. Here we show that WOX4 acts redundantly with WOX14 in the regulation of vascular cell division, but that these genes have no function in regulating vascular organisation. Furthermore, we identify an interaction between PXY and the receptor kinase ERECTA (ER) that affects the organisation of the vascular tissue but not the rate of cell division, suggesting that cell division and vascular organisation are genetically separable. Our observations also support a model whereby tissue organisation and cell division are integrated via PXY and ER signalling, which together coordinate development of different cell types that are essential for normal stem formation.
登录
查看更多内容
影响因子：
56.9
作者：
Fletcher, LC;Brand, U;Meyerowitz, EM
通讯作者：
Meyerowitz, EM
影响因子：
9.2
作者：
Hunt, Lee;Gray, Julie E.
通讯作者：
Gray, Julie E.
DOI：
10.1002/dvg.1020160409
发表时间：
1995-01-01
期刊：
DEVELOPMENTAL GENETICS
影响因子：
--
作者：
MCCONNELL, JR;BARTON, MK
通讯作者：
BARTON, MK
影响因子：
7.2
作者：
Clough, SJ;Bent, AF
通讯作者：
Bent, AF
影响因子：
9.2
作者：
Fisher, Kate;Turner, Simon
通讯作者：
Turner, Simon