Traumatic events: exploring associations with maternal depression, infant bonding, and oxytocin in Latina mothers.
Traumatic events: exploring associations with maternal depression, infant bonding, and oxytocin in Latina mothers.
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DOI：
10.1186/s12905-018-0520-5
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发表时间：
2018-02-01
期刊：
影响因子：
--
通讯作者：
Ravat U
中科院分区：
文献类型：
--
作者：
Lara-Cinisomo S;Zhu K;Fei K;Bu Y;Weston AP;Ravat U
童年和成年期的创伤经历会对母婴关系产生负面影响，并增加产后抑郁症（PPD）的风险。较低的催产素水平也与产后抑郁症和母婴关系受损有关。尽管这些研究领域取得了进展，但大部分研究都没有包括拉丁裔，而拉丁裔很重要，因为他们的生育率、创伤事件和PPD发生率很高。为了解决文献中发现的差距，我们探讨了创伤性生活事件、PPD和结合子量表评分（例如，受损的债券，拒绝和愤怒，焦虑的照顾）在一个样本的28个拉丁裔。我们还研究了这些因素和催产素（OT）之间的关联。采用Wilcoxon符号秩检验检查子量表评分随时间的差异。Kruskal-Wallis单因素方差分析被用来检查母亲抑郁状态和创伤事件的结合分量表得分和OT的差异。我们还探讨了创伤性事件和OT AUC对结合子量表评分的交互作用。8周时患有PPD的女性的拒绝和愤怒子量表评分（p = 0.054）显著高于非PPD女性，其中评分越高代表关系越不牢固。在产后8周时，观察到成年创伤史的拒绝和愤怒（p = 0.042）和护理焦虑（p = 0.005）的显着差异。在产后4周的护理焦虑评分（p = 0.024）和产后8周的亲密关系受损评分（p = 0.041）中，涉及婴儿的创伤事件也存在显著差异。OT和儿童期性虐待对受损的联系有显著的相互作用（p = 0.038）。我们观察到不同的反应，在债券分量表分数的创伤历史。经历过涉及婴儿的创伤的女性有更高的受损的联系得分，而那些有成年创伤史的女性，如亲密伴侣暴力，得分较低。我们还发现了童年创伤和催产素水平之间的相互作用对结合分数，这表明对早期虐待的生理反应可能对母亲的结合感知产生影响。这些初步结果表明，需要进一步研究分娩前发生的创伤性事件的长期情感和生理影响。
Childhood and adulthood traumatic experiences negatively impact maternal-infant bonding and increase risk of postpartum depression (PPD). Lower oxytocin levels have also been associated with PPD and compromised mother-infant bonding. Despite advances in these areas of investigation, much of the research has not included Latinas, who are important because they have high rates of fertility, traumatic events, and PPD. To address gaps identified in the literature, we explored associations between traumatic life events, PPD, and bonding subscale scores (e.g., Impaired Bonding, Rejection and Anger, Anxiety about Care) in a sample of 28 Latinas. We also examined associations between these factors and oxytocin (OT). Wilcoxon signed-rank tests were employed to examine differences in subscale scores over time. Kruskal–Wallis one-way analysis of variance was used to examine differences in bonding subscale scores and OT by maternal depression status and traumatic events. We also explored interaction effects of traumatic events and OT AUC on bonding subscale scores. Women with PPD at 8 weeks had significantly higher Rejection and Anger subscale scores (p = 0.054) than non-PPD women, where higher scores represent more compromised bonding. Significant differences in Rejection and Anger (p = 0.042) and Anxiety about Care (p = 0.005) by adulthood traumatic histories were observed at 8 weeks postpartum. There was also a significant difference in Anxiety about Care scores at 4 weeks postpartum (p = 0.024) and Impaired Bonding at 8 weeks postpartum (p = 0.041) by trauma events involving an infant. There was a significant interaction between OT and childhood sexual abuse on Impaired Bonding (p = 0.038). We observed differential responses in bonding subscale scores by traumatic histories. Women who experienced a trauma involving an infant had higher compromised bonding scores, whereas those with adulthood traumatic histories, such as intimate partner violence, had lower scores. We also found an interaction between childhood trauma and oxytocin levels on bonding scores, suggesting a physiological response to early abuse that can have implications on mothers’ bonding perceptions. These preliminary results suggest the need for additional research on the long-term emotional and physiological effects of traumatic events occurring prior to parturition.
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