Cilia in different segments of the rat nephron.
Cilia in different segments of the rat nephron.
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DOI：
10.1083/jcb.11.1.248
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发表时间：
1961-10
期刊：
影响因子：
--
通讯作者：
MADDEN SC
中科院分区：
文献类型：
--
作者：
LATTA H;MAUNSBACH AB;MADDEN SC
DISCUSSIONThe observation of various characteristic components of kinocilia (11)(rather than stereocilia (9)) leaves no doubt as to their identity. It also confirms their being found in mammalian kidney by light microscopy and their being described as solitary and centrally placed in the renal cells (16). The basal body and associated structures vary among species, with mammalian cilia appearing to form a separate group (3, 12). The infrequency of cilia in the mammalian metanephric kidney is further attested by the fact that they are rarely found with light (16) or electron (5) microscopy. It was necessary to study a very large number of sections in this laboratory in the past year to collect the observations reported here.It is difficult to suggest a function for such rare cilia in the mammalian kidney. Perhaps they serve to create turbulence and prevent laminar flow of tubular fluid, thereby facilitating the resorption of solutes. They may also be viewed as an evolutionary remnant because they are found much more frequently in the excretory ducts of lower animals (15). Cilia are numerous in the frog kidney and have been reported in electron microscopic studies (1, 3). Although they may develop considerable pressure in the frog kidney (3), the cilia of the mammalian kidney could hardly propel much fluid. The present observations offer more evidence in support of a common embryologic origin of cells in different tubular segments. However, cilia have not yet been found in embryologic studies of rat kidneys (2, 14). The observation of large groups of cilia in a renal carcinoma of hamsters (but not in normal hamster kidney)(7) is remarkable. This suggests that if dedifferentiation is associated with neoplasia it can still evoke highly differentiated structures from an early evolutionary period.
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用电子显微镜研究的新生小鼠肾脏中的细胞分化。
DOI：
10.1083/jcb.3.3.349
发表时间：
1957-05-25
期刊：
The Journal of biophysical and biochemical cytology
影响因子：
--
作者：
CLARK SL Jr
通讯作者：
CLARK SL Jr
DOI：
10.1007/bf00345847
发表时间：
1956-01-01
期刊：
ZEITSCHRIFT FUR ZELLFORSCHUNG UND MIKROSKOPISCHE ANATOMIE
影响因子：
--
作者：
RHODIN, J;DALHAMN, T
通讯作者：
DALHAMN, T
影响因子：
1.5
作者：
FAWCETT, DW;PORTER, KR
通讯作者：
PORTER, KR
DOI：
10.1016/s0022-5320(60)80033-0
发表时间：
1960-01-01
期刊：
JOURNAL OF ULTRASTRUCTURE RESEARCH
影响因子：
--
作者：
LATTA, H;MAUNSBACH, AB;MADDEN, SC
通讯作者：
MADDEN, SC
DOI：
10.1016/s0022-5320(57)80004-5
发表时间：
1957-01-01
期刊：
JOURNAL OF ULTRASTRUCTURE RESEARCH
影响因子：
--
作者：
MANNWEILER, K;BERNHARD, W
通讯作者：
BERNHARD, W