Phenotypes of adults with congenital heart disease around the globe: a cluster analysis.
Phenotypes of adults with congenital heart disease around the globe: a cluster analysis.
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DOI：
10.1186/s12955-021-01696-x
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发表时间：
2021-02-10
影响因子：
3.6
通讯作者：
APPROACH-IS consortium and the International Society for Adult Congenital Heart Disease (ISACHD)
中科院分区：
文献类型：
--
作者：
Callus E;Pagliuca S;Boveri S;Ambrogi F;Luyckx K;Kovacs AH;Apers S;Budts W;Enomoto J;Sluman MA;Wang JK;Jackson JL;Khairy P;Cook SC;Chidambarathanu S;Alday L;Eriksen K;Dellborg M;Berghammer M;Johansson B;Mackie AS;Menahem S;Caruana M;Veldtman G;Soufi A;Fernandes SM;White K;Kutty S;Moons P;APPROACH-IS consortium and the International Society for Adult Congenital Heart Disease (ISACHD)
为成人先天性心脏病(ACHD)患者在感知健康、心理功能、健康行为和生活质量(QOL)方面得出基于聚类分析的分组。这项研究是一项名为PROCESS-IS的更大的全球多中心研究的一部分；这是一项横断面研究，招募了来自15个参与国家的4028名患者(2013-2015)。采用Ward‘s方法对心理特征相似的患者进行分层聚类分析，将心理特征相似的患者分组，并考虑以下测验的得分：连贯感、健康行为量表(体育锻炼得分)、医院焦虑抑郁量表、疾病知觉问卷、生活满意度量表和EQ-5D感知健康量表的视觉模拟量表得分以及测量生活质量的线性模拟量表(0~100)的得分。资料完整的3768例患者分为3组。在分析中，第一组和第二组代表了89.6%的患者，他们报告了良好的健康感知、生活质量、心理功能和最大的运动量。第三组中的患者在所有PRO中的得分都显著较低。这一集群的特点是女性比例明显更高，平均年龄更高，教育水平最低，先天性心脏病的形式更复杂，医疗合并症更多。这项研究表明，某些人口统计学和临床特征可能与ACHD患者较差的健康认知、生活质量、心理功能和健康行为有关。这些信息可用于改进心理社会筛查和及时提供心理社会护理。
To derive cluster analysis-based groupings for adults with congenital heart disease (ACHD) when it comes to perceived health, psychological functioning, health behaviours and quality of life (QoL). This study was part of a larger worldwide multicentre study called APPROACH-IS; a cross sectional study which recruited 4028 patients (2013–2015) from 15 participating countries. A hierarchical cluster analysis was performed using Ward's method in order to group patients with similar psychological characteristics, which were defined by taking into consideration the scores of the following tests: Sense Of Coherence, Health Behavior Scale (physical exercise score), Hospital Anxiety Depression Scale, Illness Perception Questionnaire, Satisfaction with Life Scale and the Visual Analogue Scale scores of the EQ-5D perceived health scale and a linear analogue scale (0–100) measuring QoL. 3768 patients with complete data were divided into 3 clusters. The first and second clusters represented 89.6% of patients in the analysis who reported a good health perception, QoL, psychological functioning and the greatest amount of exercise. Patients in the third cluster reported substantially lower scores in all PROs. This cluster was characterised by a significantly higher proportion of females, a higher average age the lowest education level, more complex forms of congenital heart disease and more medical comorbidities. This study suggests that certain demographic and clinical characteristics may be linked to less favourable health perception, quality of life, psychological functioning, and health behaviours in ACHD. This information may be used to improve psychosocial screening and the timely provision of psychosocial care.
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影响因子：
24
作者：
Apers, Silke;Kovacs, Adrienne H.;Moons, Philip
通讯作者：
Moons, Philip
影响因子：
37.8
作者：
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通讯作者：
Gewillig, Marc
影响因子：
8.3
作者：
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通讯作者：
Hager, Alfred
影响因子：
2.9
作者：
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通讯作者：
Budts, Werner
影响因子：
2.9
作者：
Apers, Silke;Moons, Philip;Budts, Werner
通讯作者：
Budts, Werner