Changes in stimulant drug use over time in the MACS: evidence for resilience against stimulant drug use among men who have sex with men.

Changes in stimulant drug use over time in the MACS: evidence for resilience against stimulant drug use among men who have sex with men.
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DOI:
10.1007/s10461-010-9866-x
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发表时间:
2012-01
期刊:
影响因子:
4.4
通讯作者:
Plankey, Michael
Plankey, Michael
中科院分区:
医学2区
文献类型:
--
作者:
Lim, Sin How;Ostrow, David;Stall, Ron;Chmiel, Joan;Herrick, Amy;Shoptaw, Steve;Kao, Uyen;Carrico, Adam;Plankey, Michael

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使用兴奋剂与男男性行为者(MSM)的许多健康问题有关。本文描述了从2003年到2008年的四年半时间里兴奋剂药物使用的变化。参与者是来自多中心艾滋病队列研究(MACS)的2,389名男性(17,222人访问)-一项正在进行的MSM艾滋病毒感染前瞻性研究。对这些男性在研究期间的数据进行基于组的轨迹分析,得出了四组解决方案:一致的用户(9.8%),使用增加的男性(5.4%),使用减少的男性(6.9%)和禁欲或很少使用的男性(77.9%)。两组在人口统计学、行为风险和HIV血清状态方面存在显著差异。随着时间的推移,增加或减少兴奋剂药物使用的男性报告了性风险的一致变化。随着时间的推移,性风险水平与兴奋剂药物使用平行,这一事实表明,找到降低MSM中兴奋剂药物使用率的方法可能是预防艾滋病毒的一种工具。
Stimulant drug use is associated with numerous health problems among men who have sex with men (MSM). This paper describes how stimulant drug use changes over a four and one-half year period from 2003 until 2008. Participants were 2,389 men (17,222 person-visits) from The Multicenter AIDS Cohort Study (MACS)—an ongoing, prospective study of HIV infection among MSM. Group-based trajectory analyses of data from these men over the study period yielded a four groups solution: consistent users (9.8%), men whose use increased (5.4%), men whose use declined (6.9%), and abstinent or rarely-using men (77.9%). There were significant differences between groups in terms of demographic, behavioral risk and HIV serostatus. Men who increased or decreased stimulant drug use over time reported congruent changes in sexual risk taking. The fact that sexual risk levels parallel stimulant drug use over time suggests that finding ways to lower rates of stimulant drug use among MSM could be a tool in HIV prevention.
水晶甲基苯丙胺的使用预测与在网上招募的男性发生性关系的男性中的事件感染:一项嵌套的病例对照研究。
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