Comparative study of pulpal responses to ProRoot MTA, Vitapex, and Metapex in canine teeth.
Comparative study of pulpal responses to ProRoot MTA, Vitapex, and Metapex in canine teeth.
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DOI：
10.1016/j.jds.2020.12.011
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发表时间：
2021-10
影响因子：
3.5
通讯作者：
Song JS
中科院分区：
文献类型：
--
作者：
Kwon W;Kim IH;Kang CM;Kim B;Shin Y;Song JS
ProRoot MTA、Vitapex和Metapex被广泛用于乳牙的牙髓治疗。本研究的目的是在犬活髓切断模型中比较ProRoot MTA、Vitapex和Metapex的牙髓反应。对34颗牙齿（21颗切牙和13颗前磨牙）进行了活髓切断术，并将ProRoot MTA，Vitapex或Metapex应用于人工暴露的牙髓组织。13周后，拔牙，苏木精-伊红染色进行组织学评价。对所有标本进行了与钙化屏障、炎症反应相关的几个类别的评价，并测量了钙化屏障形成的面积。ProRoot MTA组中的大多数样本在牙髓切断部位形成钙化屏障，并显示出低水平的炎症反应。然而，与ProRoot MTA组相比，Vitapex和Metapex组形成了少量钙化屏障。这项体内研究发现，Vitapex和Metapex诱导了相似的牙髓反应，但与使用ProRoot MTA相比，结果较差。因此，Vitapex和Metapex在直接盖髓和活髓切断术中不是ProRoot MTA的良好替代品。
ProRoot MTA, Vitapex, and Metapex are widely used for pulp treatment of primary tooth. The aim of this study was to compare the pulpal responses to ProRoot MTA, Vitapex, and Metapex in a canine model of pulpotomy. Pulpotomy procedure was performed to 34 teeth (21 incisors and 13 premolars) and ProRoot MTA, Vitapex or Metapex was applicated to artificially exposed pulp tissues. After 13 weeks, the teeth were extracted and processed with hematoxylin-eosin staining for histologic evaluation. All specimens were evaluated in several categorys related to calcific barrier, inflammatory responses and the area of calcific barrier formation was measured. Most of the specimens in the ProRoot MTA group developed a calcific barrier at the pulp amputation site and showed a low level of inflammatory response. However, in comparison to ProRoot MTA group, a small amount of calcific barrier formed in Vitapex and Metapex groups. This in vivo study found that Vitapex and Metapex induced similar pulpal responses but showed poor outcomes compared with using ProRoot MTA. Vitapex and Metapex are therefore not good substitutes for ProRoot MTA in direct pulp capping and pulpotomy.
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DOI：
10.1016/0030-4220(82)90220-1
发表时间：
1982-01-01
影响因子：
--
作者：
MANHART, MJ
通讯作者：
MANHART, MJ
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发表时间：
1972-01-01
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通讯作者：
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DOI：
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期刊：
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影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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影响因子：
5
作者：
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通讯作者：
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