Borrelia burgdorferi has minimal impact on the Lyme disease reservoir host Peromyscus leucopus.
Borrelia burgdorferi has minimal impact on the Lyme disease reservoir host Peromyscus leucopus.
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伯氏疏螺旋体对莱姆病储存宿主白鼠白鼠 (Peromyscus leucopus) 的影响极小。
DOI：
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
R. Ostfeld
中科院分区：
文献类型：
--
作者：
L. Schwanz;M. Voordouw;Dustin Brisson;R. Ostfeld
The epidemiology of vector-borne zoonotic diseases is determined by encounter rates between vectors and hosts. Alterations to the behavior of reservoir hosts caused by the infectious agent have the potential to dramatically alter disease transmission and human risk. We examined the effect of Borrelia burgdorferi, the etiological agent of Lyme disease, on one of its most important reservoir hosts, the white-footed mouse, Peromyscus leucopus. We mimic natural infections in mice using the vector (Black-legged ticks, Ixodes scapularis) and examine the immunological and behavioral responses of mouse hosts. Despite producing antibodies against B. burgdorferi, infected mice did not have elevated white blood cells compared with uninfected mice. In addition, infected and uninfected mice did not differ in their wheel-running activity. Our results suggest that infection with the spirochete B. burgdorferi has little impact on the field activity of white-footed mice. Lyme disease transmission appears to be uncomplicated by pathogen-altered behavior of this reservoir host.
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DOI：
--
发表时间：
1991-08
期刊：
The American journal of pathology
影响因子：
--
作者：
S. Barthold;D. Persing;Audrey L. Armstrong;Ruth A. Peeples
通讯作者：
S. Barthold;D. Persing;Audrey L. Armstrong;Ruth A. Peeples
共感染伯氏疏螺旋体和田鼠巴贝斯虫的小鼠关节炎严重程度增加。
DOI：
10.1086/341452
发表时间：
2002
期刊：
The Journal of infectious diseases.
影响因子：
--
作者：
Moro,ManuelH;Zegarra-Moro,OfeliaL;Bjornsson,Johannes;Hofmeister,ErikK;Bruinsma,Elizabeth;Germer,JeffreyJ;Persing,DavidH
通讯作者：
Persing,DavidH
通过行为指标将疾病与群落生态联系起来：白足小鼠的免疫挑战及其生态影响。
DOI：
10.1111/j.1365-2656.2010.01745.x
发表时间：
2011
期刊：
The Journal of animal ecology
影响因子：
--
作者：
Schwanz,LisaE;Brisson,Dustin;Gomes-Solecki,Maria;Ostfeld,RichardS
通讯作者：
Ostfeld,RichardS
严格伯氏疏螺旋体当地群体中 ospC 的遗传多样性。
影响因子：
3.3
作者：
Wang,IN;Dykhuizen,DE;Qiu,W;Dunn,JJ;Bosler,EM;Luft,BJ
通讯作者：
Luft,BJ
橡子产量和小鼠丰度对若虫肩胛硬蜱蜱丰度和伯氏疏螺旋体感染流行率的影响。
DOI：
10.1089/153036601750137688
发表时间：
2001
期刊：
Vector borne and zoonotic diseases (Larchmont, N.Y.)
影响因子：
--
作者：
Ostfeld,RS;Schauber,EM;Canham,CD;Keesing,F;Jones,CG;Wolff,JO
通讯作者：
Wolff,JO