Microbial interactions in building of communities.

Microbial interactions in building of communities.
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DOI:
10.1111/omi.12012
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发表时间:
2013-04
影响因子:
3.7
通讯作者:
Jenkinson HF
Jenkinson HF
中科院分区:
医学3区
文献类型:
--
作者:
Wright CJ;Burns LH;Jack AA;Back CR;Dutton LC;Nobbs AH;Lamont RJ;Jenkinson HF

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Establishment of a community is considered to be essential for microbial growth and survival in the human oral cavity. Biofilm communities have increased resilience to physical forces, antimicrobial agents, and nutritional variations. Specific cell-to-cell adherence processes, mediated by adhesin-receptor pairings on respective microbial surfaces, are able to direct community development. These interactions co-localize species in mutually beneficial relationships, such as streptococci, veillonellae, Porphyromonas gingivalis and Candida albicans. In transition from the planktonic mode of growth to a biofilm community, microorganisms undergo major transcriptional and proteomic changes. These occur in response to sensing of diffusible signals, such as autoinducer molecules, and to contact with host tissues or other microbial cells. Underpinning many of these processes are intracellular phosphorylation events that regulate a large number of microbial interactions relevant to community formation and development.
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