Reduced growth hormone signaling and methionine restriction: interventions that improve metabolic health and extend life span.
Reduced growth hormone signaling and methionine restriction: interventions that improve metabolic health and extend life span.
复制标题
减少生长激素信号传导和蛋氨酸限制：改善代谢健康并延长寿命的干预措施。
DOI：
10.1111/nyas.12971
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发表时间：
2016-01
影响因子：
5.2
通讯作者：
Brown-Borg HM
中科院分区：
文献类型：
--
作者：
Brown-Borg HM
Interventions that improve health are often associated with longevity. Reduced growth hormone signaling has been shown to increase life span in mice by over 50%. Similarly, reductions in dietary intake of methionine, in rats and mice, result in life-span extension. Many factors affect metabolic health, mitochondrial function, and resistance to stressors, each of which influence aging and life span. This paper presents a comparison of these two interventions, as well as the results of a study combining these interventions, to understand potential mechanisms underlying their effectiveness in enhancing healthy aging.
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DOI：
10.1186/2046-2395-3-10
发表时间：
2014
期刊：
Longevity & healthspan
影响因子：
--
作者：
Brown-Borg HM;Rakoczy S;Wonderlich JA;Armstrong V;Rojanathammanee L
通讯作者：
Rojanathammanee L
影响因子：
3.9
作者：
Bartke, Andrzej
通讯作者：
Bartke, Andrzej
影响因子：
4.8
作者：
Al-Regaiey, KA;Masternak, MM;Bartke, A
通讯作者：
Bartke, A
影响因子：
64.8
作者：
Bartke, A;Wright, JC;Roth, GS
通讯作者：
Roth, GS
影响因子：
4.5
作者：
Caro, Pilar;Gomez, Jose;Barja, Gustavo
通讯作者：
Barja, Gustavo