The transcriptional landscape of Arabidopsis thaliana pattern-triggered immunity
The transcriptional landscape of Arabidopsis thaliana pattern-triggered immunity
复制标题
拟南芥模式触发免疫的转录景观
DOI：
10.1101/2020.11.30.404566
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Bjornson M
中科院分区：
文献类型：
--
作者：
Bjornson M
植物根据环境条件调整自己的新陈代谢，部分是通过识别一系列广泛的自我和非自我分子。特别是，细胞表面定位的模式识别受体（PRRs）对微生物或植物源分子模式的感知会诱导模式触发免疫，其中包括大量的转录重编程。越来越多的植物PRRs和相应的配体是已知的，但植物是否根据不同的生物起源或不同的生化性质调整其免疫输出仍然不清楚。在这里，我们在早期时间序列中进行了详细的转录组学分析，重点研究了模式植物拟南芥（arabidopsis thaliana）中良好特征模式诱导的快速信号转录输出。这表明，对不同模式的转录反应（与它们的起源、生化性质或PRR类型无关）是非常一致的。此外，许多最快速和最常见的被模式上调的基因也被非生物胁迫诱导，这表明对模式的早期转录反应是植物一般应激反应（GSR）的一部分。因此，植物细胞的反应首先是对危险的反应。值得注意的是，GSR的遗传损伤降低了模式诱导的抗菌免疫，证实了这种初始危险反应的生物学相关性。重要的是，对模式反应常见和特异性的一小部分“核心免疫反应”基因的定义揭示了以前未被表征的谷氨酸受体样（GLR）钙渗透通道在免疫中的功能。因此，该研究阐明了早期免疫转录重编程的一般和独特特性，并揭示了植物免疫的重要组成部分。
Plants tailor their metabolism to environmental conditions, in part through the recognition of a wide array of self and non-self molecules. In particular, the perception of microbial or plant-derived molecular patterns by cell-surface-localized pattern recognition receptors (PRRs) induces pattern-triggered immunity, which includes massive transcriptional reprogramming. An increasing number of plant PRRs and corresponding ligands are known, but whether plants tune their immune outputs to patterns of different biological origins or of different biochemical natures remains mostly unclear. Here, we performed a detailed transcriptomic analysis in an early time series focused to study rapid-signalling transcriptional outputs induced by well-characterized patterns in the model plantArabidopsis thaliana. This revealed that the transcriptional responses to diverse patterns (independent of their origin, biochemical nature or type of PRR) are remarkably congruent. Moreover, many of the genes most rapidly and commonly upregulated by patterns are also induced by abiotic stresses, suggesting that the early transcriptional response to patterns is part of the plant general stress response (GSR). As such, plant cells’ response is in the first instance mostly to danger. Notably, the genetic impairment of the GSR reduces pattern-induced antibacterial immunity, confirming the biological relevance of this initial danger response. Importantly, the definition of a small subset of ‘core immunity response’ genes common and specific to pattern response revealed the function of previously uncharacterized GLUTAMATE RECEPTOR-LIKE (GLR) calcium-permeable channels in immunity. This study thus illustrates general and unique properties of early immune transcriptional reprogramming and uncovers important components of plant immunity.
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影响因子：
3.5
作者：
Goehre, Vera;Jones, Alexandra M. E.;Weber, Andreas P. M.
通讯作者：
Weber, Andreas P. M.
DOI：
10.1094/mpmi-03-13-0077-r
发表时间：
2013-09
期刊：
Molecular plant-microbe interactions : MPMI
影响因子：
--
作者：
Lorek J;Griebel T;Jones AM;Kuhn H;Panstruga R
通讯作者：
Panstruga R
水稻长链非编码RNA多聚腺苷酸化的应激反应调控
影响因子：
7.2
作者：
Saijo, Yusuke;Loo, Eliza Po-iian;Yasuda, Shigetaka
通讯作者：
Yasuda, Shigetaka
影响因子：
10.2
作者：
Yu X;Feng B;He P;Shan L
通讯作者：
Shan L
影响因子：
3.8
作者：
Ridley, BL;O'Neill, MA;Mohnen, DA
通讯作者：
Mohnen, DA