Regenerating functional heart tissue for myocardial repair.
Regenerating functional heart tissue for myocardial repair.
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DOI：
10.1007/s00018-012-0942-4
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发表时间：
2012-08
影响因子：
8
通讯作者：
Qyang, Yibing
中科院分区：
文献类型：
--
作者：
Alcon, Andre;Bozkulak, Esra Cagavi;Qyang, Yibing
关键词：
Heart disease is one of the leading causes of death worldwide and the number of patients with the disease is likely to grow with the continual decline in health for most of the developed world. Heart transplantation is one of the only treatment options for heart failure due to an acute myocardial infarction, but limited donor supply and organ rejection limit its widespread use. Cellular cardiomyoplasty, or cellular implantation, combined with various tissue-engineering methods aims to regenerate functional heart tissue. This review highlights the numerous cell sources that have been used to regenerate the heart as well as cover the wide range of tissue-engineering strategies that have been devised to optimize the delivery of these cells. It will probably be a long time before an effective regenerative therapy can make a serious impact at the bedside.
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DOI：
10.1152/ajpheart.1999.277.2.h433
发表时间：
1999-08-01
影响因子：
4.8
作者：
Bursac, N;Papadaki, M;Freed, LE
通讯作者：
Freed, LE