Toxicological profile of chlorophenols and their derivatives in the environment: the public health perspective.
Toxicological profile of chlorophenols and their derivatives in the environment: the public health perspective.
复制标题
DOI：
10.1155/2013/460215
复制
发表时间：
2013
影响因子：
--
通讯作者：
Idemudia OG
中科院分区：
文献类型：
--
作者：
Igbinosa EO;Odjadjare EE;Chigor VN;Igbinosa IH;Emoghene AO;Ekhaise FO;Igiehon NO;Idemudia OG
氯酚类化合物及其衍生物是环境中普遍存在的污染物。这些化合物用作制造农业化学品、药物、杀生物剂和染料的中间体。氯酚通过各种来源进入环境，如工业废物，杀虫剂和杀虫剂，或通过复杂的氯化烃降解。氯酚的热降解和化学降解导致形成构成公共卫生问题的有害物质。这些化合物可能导致人类和动物的组织病理学改变、遗传毒性、致突变性和致癌性以及其他异常。此外，氯酚类化合物降解的难降解性构成了环境公害，需要很好地了解这些化合物及其衍生物的归宿和迁移，以便更清楚地了解对人类和动物的相关风险和致病机制。本文综述了氯酚及其衍生物，探讨了目前研究的影响，对公众健康，并提出了缓解措施。
Chlorophenol compounds and their derivatives are ubiquitous contaminants in the environment. These compounds are used as intermediates in manufacturing agricultural chemicals, pharmaceuticals, biocides, and dyes. Chlorophenols gets into the environment from a variety of sources such as industrial waste, pesticides, and insecticides, or by degradation of complex chlorinated hydrocarbons. Thermal and chemical degradation of chlorophenols leads to the formation of harmful substances which constitute public health problems. These compounds may cause histopathological alterations, genotoxicity, mutagenicity, and carcinogenicity amongst other abnormalities in humans and animals. Furthermore, the recalcitrant nature of chlorophenolic compounds to degradation constitutes an environmental nuisance, and a good understanding of the fate and transport of these compounds and their derivatives is needed for a clearer view of the associated risks and mechanisms of pathogenicity to humans and animals. This review looks at chlorophenols and their derivatives, explores current research on their effects on public health, and proffers measures for mitigation.
登录
查看更多内容
影响因子：
3.2
作者：
Andersson, MA;Hellman, BE
通讯作者：
Hellman, BE
影响因子：
8.8
作者：
Abhilash, P. C.;Singh, Nandita
通讯作者：
Singh, Nandita
影响因子：
4.5
作者：
Brodeur, JC;Dixon, DG;McKinley, RS
通讯作者：
McKinley, RS
影响因子：
6.8
作者：
Carrizo, Daniel;Grimalt, Joan O.;Sunyer, Jordi
通讯作者：
Sunyer, Jordi
影响因子：
4
作者：
CLINE, RE;HILL, RH;NEEDHAM, LL
通讯作者：
NEEDHAM, LL