Feasibility and acceptability of a Tai Chi Chih randomized controlled trial in senior female cancer survivors.

Feasibility and acceptability of a Tai Chi Chih randomized controlled trial in senior female cancer survivors.
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DOI:
10.1177/1534735413485418
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发表时间:
2013-11
影响因子:
2.9
通讯作者:
Kinney AY
Kinney AY
中科院分区:
医学3区
文献类型:
--
作者:
Campo RA;O'Connor K;Light KC;Nakamura Y;Lipschitz DL;LaStayo PC;Pappas L;Boucher K;Irwin MR;Agarwal N;Kinney AY

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太极拳 (TCC) 可以改善乳腺癌幸存者和健康老年人的身体机能和心理益处;因此,对于身体机能下降的老年癌症幸存者也可能有益。这项随机对照试验 (RCT) 的目的是检验太极拳 (TCC) 干预对身体功能受限的老年女性癌症幸存者的可行性和可接受性,以及其对生活质量的影响。这是一个双臂平行组随机对照试验,为期 12 周的太极拳或健康教育控制。 63 名身体功能受限(SF-12 健康调查角色身体和身体功能分量表)的老年(M 年龄=67 岁,SD=7.15)女性癌症幸存者(83% 乳腺癌,I-III 期)被随机分配接受为期 12 周的 TCC 或健康教育对照 (HEC)。主要结果是可行性和可接受性。次要结果包括生活质量(SF-36 健康调查)和参与者对干预的定性反馈。两个研究组的保留率(TCC = 91%;HEC = 81%)和出勤率(TCC = 79%;HEC = 83%)和满意度都很高,但彼此之间没有显着差异。干预后一周,TCC 组和 HEC 组之间的 SF-36 评分没有差异。组内分析显示,TCC 的心理成分总分有显着改善(p = 0.01),但 HEC 则没有。定性分析表明,TCC 组认为他们获得了精神和身体上的好处,而 HEC 组则报告了社会支持福利和收到的信息。 TCC 干预被发现对于老年女性癌症幸存者来说是一种可行且可接受的方式。未来,需要更大规模的确定性试验来阐明 TCC 剂量对这一弱势群体生活质量的影响。
Tai Chi Chih (TCC) is associated with improved physical functioning and psychological benefits in breast cancer survivors and healthy older adults; thus, may also be beneficial for senior cancer survivors with physical functioning declines. The purpose of this randomized controlled trial (RCT) was to examine the feasibility and acceptability of a Tai Chi Chih (TCC) intervention in senior female cancer survivors, with physical functioning limitations, as well as, its effects on QOL. This was a two-armed, parallel group, RCT with 12-weeks of Tai Chi Chih or Health Education Control. Sixty-three senior (M age=67 years, SD=7.15) female cancer survivors (83% breast cancer, stages I–III) with physical functioning limitations (SF-12 Health Survey role physical & physical functioning subscales) were randomized to 12-weeks of TCC or Health Education control (HEC). Primary outcomes were feasibility and acceptability. Secondary outcomes included quality of life (SF-36 Health Survey), and participants’ qualitative feedback on intervention. Retention (TCC = 91%; HEC = 81%) and class attendance (TCC =79%; HEC = 83%) rates, and satisfaction levels for both study arms were high, but did not significantly differ from one another. At one-week post-intervention, none of the SF-36 scores differed between the TCC and HEC arms. Within-group analyses revealed significant improvements in the mental component summary score in TCC (p = 0.01), but not in HEC. Qualitative analyses indicated that the TCC group felt they received mental and physical benefits, whereas HEC group reported on social support benefits and information received. A TCC intervention was found to be a feasible and acceptable modality for senior female cancer survivors. Future, larger definitive trials are needed to clarify TCC dosage effects on QOL in this vulnerable population.
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