Nasal NK/T-cell lymphoma: epidemiology and pathogenesis.

Nasal NK/T-cell lymphoma: epidemiology and pathogenesis.
复制标题

DOI:
10.1007/s12185-008-0021-7
复制
发表时间:
2008-03
影响因子:
2.1
通讯作者:
Yang, Woo-Ick
Yang, Woo-Ick
中科院分区:
医学4区
文献类型:
--
作者:
Aozasa, Katsuyuki;Takakuwa, Tetsuya;Hongyo, Tadashi;Yang, Woo-Ick

文献摘要

参考文献

被引文献

相似文献

鼻NK/T细胞淋巴瘤(NKTCL)是一种罕见的疾病,但通常表现出高度侵袭性的临床过程。这种疾病在亚洲和拉丁美洲国家比在西方国家更常见,并且普遍与EB病毒(EBV)感染有关。基因突变分析,特别是p53和c-KIT,揭示了不同地区的频率。流行病学研究揭示了1977-1989年至1990-1996年期间韩国疾病频率的变化。病例对照研究表明,接触农药和化学溶剂可能是NKTCL的病因。进一步研究包括患者的HLA抗原分型是必要的,以进一步阐明疾病的机制。
Nasal NK/T-cell lymphoma (NKTCL) is an uncommon disease, but usually shows a highly aggressive clinical course. The disease is much more frequent in Asian and Latin American countries than in Western countries, and is universally associated with Epstein–Barr virus (EBV) infection. Analyses of gene mutations, especially p53 and c-KIT, revealed the different frequencies by district. Epidemiological studies revealed the changes of the disease frequency in Korea during the period from 1977–1989 to 1990–1996. Case-control study showed that the exposure to pesticides and chemical solvents could be causative of NKTCL. Further studies including HLA antigen typing of patients is necessary to further clarify the disease mechanism.
DOI: 10.1073/pnas.81.23.7632
发表时间: 1984-01-01
期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子: --
作者:
DAMBAUGH, T;HENNESSY, K;KIEFF, E
通讯作者: KIEFF, E
DOI: 10.1002/ijc.2910340202
发表时间: 1984-01-01
影响因子: 6.4
作者:
HO, FCS;TODD, D;KHOO, RKK
通讯作者: KHOO, RKK
DOI: 10.1097/00000478-200011000-00006
发表时间: 2000-11-01
影响因子: 5.6
作者:
Gaal, K;Sun, NCJ;Arber, DA
通讯作者: Arber, DA
DOI: 10.1200/jco.1998.16.1.70
发表时间: 1998-01-01
影响因子: 45.3
作者:
Cheung, MMC;Chan, JKC;Ngan, RKC
通讯作者: Ngan, RKC
DOI: 10.1126/science.1905840
发表时间: 1991-07-05
期刊: SCIENCE
影响因子: 56.9
作者:
HOLLSTEIN, M;SIDRANSKY, D;HARRIS, CC
通讯作者: HARRIS, CC